Compile Data Set for Download or QSAR
Report error Found 174 Enz. Inhib. hit(s) with all data for entry = 7874
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222833BDBM222833(US9315498, 124)
Affinity DataEC50:  7nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222718BDBM222718(US9315498, 5)
Affinity DataEC50:  7nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222719BDBM222719(US9315498, 6)
Affinity DataEC50:  9nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 198910BDBM198910(US9221802, Ref. Ex. 72 | US9315498, 72)
Affinity DataEC50:  10nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222831BDBM222831(US9315498, 122)
Affinity DataEC50:  11nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222794BDBM222794(US9315498, 84)
Affinity DataEC50:  11nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222828BDBM222828(US9315498, 119)
Affinity DataEC50:  11nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222746BDBM222746(US9315498, 34)
Affinity DataEC50:  11nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222789BDBM222789(US9315498, 77)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222888BDBM222888(US9315498, 174)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222775BDBM222775(US9315498, 62)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222755BDBM222755(US9315498, 43)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222735BDBM222735(US9315498, 23)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222797BDBM222797(US9315498, 87)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 198913BDBM198913(US9221802, Ref. Ex. 81 | US9315498, 81)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222834BDBM222834(US9315498, 125)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 198911BDBM198911(US9221802, Ref. Ex. 76 | US9315498, 76)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222883BDBM222883(US9315498, 169)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222884BDBM222884(US9315498, 170)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222827BDBM222827(US9315498, 118)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222824BDBM222824(US9315498, 115)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222867BDBM222867(US9315498, 153)
Affinity DataEC50:  14nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222734BDBM222734(US9315498, 22)
Affinity DataEC50:  14nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222760BDBM222760(US9315498, 48)
Affinity DataEC50:  14nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222741BDBM222741(US9315498, 29)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222722BDBM222722(US9315498, 9)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222866BDBM222866(US9315498, 152)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222882BDBM222882(US9315498, 168)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222752BDBM222752(US9315498, 40)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222739BDBM222739(US9315498, 27)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222781BDBM222781(US9315498, 67)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222771BDBM222771(US9315498, 59)
Affinity DataEC50:  16nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222754BDBM222754(US9315498, 42)
Affinity DataEC50:  16nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222721BDBM222721(US9315498, 8)
Affinity DataEC50:  17nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222785BDBM222785(US9315498, 71)
Affinity DataEC50:  17nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222818BDBM222818(US9315498, 109 | US11059766, WO2011128279 Ex. 109 ...)
Affinity DataEC50:  18nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222832BDBM222832(US9315498, 123)
Affinity DataEC50:  18nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222839BDBM222839(US9315498, 129)
Affinity DataEC50:  18nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222714BDBM222714(US9315498, 3)
Affinity DataEC50:  18nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222809BDBM222809(US9315498, 99)
Affinity DataEC50:  18nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222798BDBM222798(US9315498, 88)
Affinity DataEC50:  19nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222865BDBM222865(US9315498, 151)
Affinity DataEC50:  19nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222744BDBM222744(US9315498, 32)
Affinity DataEC50:  19nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222843BDBM222843(US9315498, 132)
Affinity DataEC50:  21nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222864BDBM222864(US9315498, 150)
Affinity DataEC50:  21nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 198912BDBM198912(US9221802, Ref. Ex. 79 | US9315498, 79)
Affinity DataEC50:  22nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222749BDBM222749(US9315498, 37)
Affinity DataEC50:  22nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222823BDBM222823(US9315498, 114)
Affinity DataEC50:  22nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222835BDBM222835(US9315498, 126)
Affinity DataEC50:  23nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 222870BDBM222870(US9315498, 156)
Affinity DataEC50:  24nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

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