Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 7544
LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50: 2.5nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200640(US9227977, Example 50)
Affinity DataIC50: 5.70nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200639(US9227977, Compound A)
Affinity DataIC50: 12nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200637(US9227977, Compound (Ia))
Affinity DataIC50: 17nMAssay Description:As a means of assessing PI3K δ activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product of PI3K&...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200639(US9227977, Compound A)
Affinity DataIC50: 25nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50: 28nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200640(US9227977, Example 50)
Affinity DataIC50: 120nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200639(US9227977, Compound A)
Affinity DataIC50: 193nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200637(US9227977, Compound (Ia))
Affinity DataIC50: 577nMAssay Description:As a means of assessing the activation of PI3K γ in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product o...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200640(US9227977, Example 50)
Affinity DataIC50: 653nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50: 4.89E+3nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50: 1.39E+4nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
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Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200637(US9227977, Compound (Ia))
Affinity DataIC50: 1.42E+4nMAssay Description:As a means of assessing PI3K alpha or beta; activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
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LigandPNGBDBM200637(US9227977, Compound (Ia))
Affinity DataIC50: 1.42E+4nMAssay Description:As a means of assessing PI3K alpha or beta; activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent