Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 7317
TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: 12nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189329(US9174940, Compound C | (+)-(1-Acetyl-4-methyl-4-p...)
Affinity DataIC50: 47nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: 48nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189327(US9174940, Compound A | Hexanoic acid (Compound A))
Affinity DataIC50: 88nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60862(BDBM189328 | US9174940, 32)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60872(US9174940, 40)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60870(US9174940, 39)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60869(US9174940, 38)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60867(US9174940, 37)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60866(US9174940, 36)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60865(US9174940, 35)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60864(US9174940, 34)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60863(US9174940, 33)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60843(US9174940, 1)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60860(US9174940, 31)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60857(US9174940, 30)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60856(US9174940, 29)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60855(US9174940, 28)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60853(US9174940, 27)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60848(US9174940, 26 | US9174940, 11)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60851(US9174940, 18)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60850(US9174940, 13)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60849(US9174940, 12)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60848(US9174940, 26 | US9174940, 11)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60847(US9174940, 7)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60845(US9174940, 6)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM60844(US9174940, 4)
Affinity DataIC50: 100nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189329(US9174940, Compound C | (+)-(1-Acetyl-4-methyl-4-p...)
Affinity DataIC50: 192nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent

TargetThyrotropin subunit beta(Bovine)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189327(US9174940, Compound A | Hexanoic acid (Compound A))
Affinity DataIC50: 368nMAssay Description:Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2016
Entry Details
Go to US Patent