Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 6949
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161045(US9108947, 20)
Affinity DataIC50: 52nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
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Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161043(US9108947, 18)
Affinity DataIC50: 65nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161046(US9108947, 21)
Affinity DataIC50: 103nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161040(US9108947, 14)
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161044(US9108947, 19)
Affinity DataIC50: 245nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161036(US9108947, 9A | US9108947, 9B)
Affinity DataIC50: 254nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161039(US9108947, 13)
Affinity DataIC50: 269nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161034(US9108947, 4)
Affinity DataIC50: 278nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161036(US9108947, 9A | US9108947, 9B)
Affinity DataIC50: 321nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161047(US9108947, 22)
Affinity DataIC50: 340nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161032(US9108947, 2)
Affinity DataIC50: 420nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161035(US9108947, 6)
Affinity DataIC50: 446nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161033(US9108947, 3)
Affinity DataIC50: 510nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161031(US9108947, 1)
Affinity DataIC50: 595nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161038(US9108947, 12)
Affinity DataIC50: 1.37E+3nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161041(US9108947, 15)
Affinity DataIC50: 1.39E+3nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161042(US9108947, 17A)
Affinity DataIC50: 1.42E+3nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM161037(US9108947, 10)
Affinity DataIC50: 2.06E+3nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent