Compile Data Set for Download or QSAR
Report error Found 334 Enz. Inhib. hit(s) with all data for entry = 7065
LigandPNGBDBM172085(US9090562, 91 | US10155002, Compound 91 | US110520...)
Affinity DataIC50: 0.520nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172163(US9090562, 171 | US10155002, Compound 171 | US1105...)
Affinity DataIC50: 0.760nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172087(US9090562, 93 | US10155002, Compound 93 | US110520...)
Affinity DataIC50: 0.870nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172176(US9175331, 61 | US9090562, 184 | EPZ009161 | US101...)
Affinity DataIC50: 0.920nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172080(US9090562, 86 | US10155002, Compound 86 | US110520...)
Affinity DataIC50: 1.12nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172138(US9175331, 16 | US9090562, 145 | EPZ007428 | US101...)
Affinity DataIC50: 1.39nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172135(US9175331, 13 | US9090562, 141 | EPZ007210 | US101...)
Affinity DataIC50: 1.51nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172089(US9090562, 95 | US10155002, Compound 95 | US110520...)
Affinity DataIC50: 1.55nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172162(US9090562, 170 | US10155002, Compound 170 | US1105...)
Affinity DataIC50: 1.63nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172181(US9090562, 189 | US10155002, Compound 189 | US1105...)
Affinity DataIC50: 1.64nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172181(US9090562, 189 | US10155002, Compound 189 | US1105...)
Affinity DataIC50: 1.82nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
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Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172135(US9175331, 13 | US9090562, 141 | EPZ007210 | US101...)
Affinity DataIC50: 1.95nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172084(US9090562, 90 | US10155002, Compound 90 | US110520...)
Affinity DataIC50: 1.99nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172088(US9090562, 94 | US10155002, Compound 94 | US110520...)
Affinity DataIC50: 2.07nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172065(US9090562, 71 | US10155002, Compound 71 | US110520...)
Affinity DataIC50: 2.19nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172173(US9090562, 181 | US10155002, Compound 181 | US1105...)
Affinity DataIC50: 2.23nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172093(US9090562, 99 | US10155002, Compound 99 | US110520...)
Affinity DataIC50: 2.37nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172088(US9090562, 94 | US10155002, Compound 94 | US110520...)
Affinity DataIC50: 2.46nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
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Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172093(US9090562, 99 | US10155002, Compound 99 | US110520...)
Affinity DataIC50: 2.56nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172087(US9090562, 93 | US10155002, Compound 93 | US110520...)
Affinity DataIC50: 2.58nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172063(US9090562, 69 | US10155002, Compound 69 | US110520...)
Affinity DataIC50: 2.60nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172161(US9090562, 169 | US10155002, Compound 169 | US1105...)
Affinity DataIC50: 2.74nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172089(US9090562, 95 | US10155002, Compound 95 | US110520...)
Affinity DataIC50: 2.77nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172076(US9090562, 82 | US10155002, Compound 82 | US110520...)
Affinity DataIC50: 2.81nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172183(US9090562, 191 | US10155002, Compound 191 | US1105...)
Affinity DataIC50: 2.82nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172166(US9175331, 28 | US9090562, 174 | EPZ008280 | US101...)
Affinity DataIC50: 2.89nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172091(US9090562, 97 | US10155002, Compound 97 | US110520...)
Affinity DataIC50: 2.96nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172074(US9090562, 80 | US10155002, Compound 80 | US110520...)
Affinity DataIC50: 3.11nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172085(US9090562, 91 | US10155002, Compound 91 | US110520...)
Affinity DataIC50: 3.15nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 3.19nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172184(US9090562, 192 | US10155002, Compound 192 | US1105...)
Affinity DataIC50: 3.22nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172072(US9090562, 78 | US10155002, Compound 78 | US110520...)
Affinity DataIC50: 3.24nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172177(US9090562, 185 | US10155002, Compound 185 | US1105...)
Affinity DataIC50: 3.38nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172091(US9090562, 97 | US10155002, Compound 97 | US110520...)
Affinity DataIC50: 3.40nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172140(US9090562, 147 | US10155002, Compound 147 | US1105...)
Affinity DataIC50: 3.44nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172069(US9090562, 75 | US10155002, Compound 75 | US110520...)
Affinity DataIC50: 3.48nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172063(US9090562, 69 | US10155002, Compound 69 | US110520...)
Affinity DataIC50: 3.49nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172076(US9090562, 82 | US10155002, Compound 82 | US110520...)
Affinity DataIC50: 3.52nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172149(US9090562, 156 | US10155002, Compound 156 | US1105...)
Affinity DataIC50: 3.57nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172084(US9090562, 90 | US10155002, Compound 90 | US110520...)
Affinity DataIC50: 3.61nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172134(US9090562, 140 | US10155002, Compound 140 | US1105...)
Affinity DataIC50: 3.69nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172070(US9090562, 76 | US10155002, Compound 76 | US110520...)
Affinity DataIC50: 3.74nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172177(US9090562, 185 | US10155002, Compound 185 | US1105...)
Affinity DataIC50: 3.74nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172183(US9090562, 191 | US10155002, Compound 191 | US1105...)
Affinity DataIC50: 3.84nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172175(US9175331, 52 | US9090562, 183 | EPZ009097 | US101...)
Affinity DataIC50: 3.87nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172074(US9090562, 80 | US10155002, Compound 80 | US110520...)
Affinity DataIC50: 3.88nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172163(US9090562, 171 | US10155002, Compound 171 | US1105...)
Affinity DataIC50: 3.97nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM172065(US9090562, 71 | US10155002, Compound 71 | US110520...)
Affinity DataIC50: 4.15nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172077(US9090562, 83 | US10155002, Compound 83 | US110520...)
Affinity DataIC50: 4.18nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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LigandPNGBDBM172164(US9090562, 172 | US10155002, Compound 172 | US1105...)
Affinity DataIC50: 4.21nMT: 2°CAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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