Compile Data Set for Download or QSAR
Report error Found 238 Enz. Inhib. hit(s) with all data for entry = 6996
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163767(US9062070, 22)
Affinity DataIC50: 40nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163826(US9062070, 81 | US9062070, 82)
Affinity DataIC50: 50nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163759(US9062070, 15)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163770(US9062070, 25)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163800(US9062070, 55 | US9062070, 56)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163826(US9062070, 81 | US9062070, 82)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163777(US9062070, 32)
Affinity DataIC50: 70nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163750(US9062070, 6 | US9062070, 7)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163765(US9062070, 20)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163766(US9062070, 21)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163776(US9062070, 31)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163794(US9062070, 49)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163828(US9062070, 83)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163850(US9062070, 105 | US9062070, 106)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163764(US9062070, 19)
Affinity DataIC50: 90nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163802(US9062070, 57)
Affinity DataIC50: 90nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163842(US9062070, 97)
Affinity DataIC50: 90nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163761(US9062070, 17 | US9062070, 17A)
Affinity DataIC50: 90nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163743(US9062070, 1C | US9062070, 1J)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163857(US9062070, 2A | US9062070, 2H | US9062070, 2G | US...)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163857(US9062070, 2A | US9062070, 2H | US9062070, 2G | US...)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163857(US9062070, 2A | US9062070, 2H | US9062070, 2G | US...)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163857(US9062070, 2A | US9062070, 2H | US9062070, 2G | US...)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163748(US9062070, 4 | US9062070, 5)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163750(US9062070, 6 | US9062070, 7)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163761(US9062070, 17 | US9062070, 17A)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163809(US9062070, 64 | US9062070, 65)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163815(US9062070, 70)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163829(US9062070, 84 | US9062070, 85)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163833(US9062070, 88)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163841(US9062070, 96A)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163847(US9062070, 102)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163770(US9062070, 25)
Affinity DataIC50: 100nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163763(US9062070, 18)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163771(US9062070, 26 | US9062070, 27)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163780(US9062070, 35 | US9062070, 36)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163785(US9062070, 40 | US9062070, 41)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163798(US9062070, 53 | US9062070, 54)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163798(US9062070, 53 | US9062070, 54)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163800(US9062070, 55 | US9062070, 56)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163848(US9062070, 103 | US9062070, 104)
Affinity DataIC50: 110nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163769(US9062070, 24)
Affinity DataIC50: 110nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163776(US9062070, 31)
Affinity DataIC50: 110nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163802(US9062070, 57)
Affinity DataIC50: 110nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163746(US9062070, 1I)
Affinity DataIC50: 120nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163771(US9062070, 26 | US9062070, 27)
Affinity DataIC50: 120nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163773(US9062070, 28 | US9062070, 29)
Affinity DataIC50: 120nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163785(US9062070, 40 | US9062070, 41)
Affinity DataIC50: 120nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163816(US9062070, 71)
Affinity DataIC50: 120nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163825(US9062070, 80)
Affinity DataIC50: 120nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
Go to US Patent

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