Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 6976
TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163037(US9061041, Compound C)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/molepH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163034(US9061041, 99)
Affinity DataKi:  60nM ΔG°:  -41.2kJ/molepH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163032(US9061041, 26)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/molepH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163036(US9061041, Compound B)
Affinity DataKi:  1.50E+3nM ΔG°:  -33.2kJ/molepH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163033(US9061041, 24)
Affinity DataKi:  4.70E+3nM ΔG°:  -30.4kJ/molepH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163035(US9061041, 93)
Affinity DataKi:  6.00E+3nM ΔG°:  -29.8kJ/molepH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent