Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 6845
TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153687(US9000015, 4 | US10507215, Compound 4)
Affinity DataIC50: 23nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
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TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153696(US9000015, 13 | US9610299, Example 13 | US10507215...)
Affinity DataIC50: 25nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153684(US9000015, 1 | US9610299, Example 1 | US10507215, ...)
Affinity DataIC50: 63nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
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TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153685(US9000015, 2 | US9610299, Example 2 | US10507215, ...)
Affinity DataIC50: 102nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153688(US9000015, 5 | US10507215, Compound 5)
Affinity DataIC50: 166nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153686(US9000015, 3 | US9610299, Example 3 | US10507215, ...)
Affinity DataIC50: 215nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153695(US9000015, 12 | US9610299, Example 12 | US10507215...)
Affinity DataIC50: 304nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153694(US9000015, 11 | US9610299, Example 11 | US10507215...)
Affinity DataIC50: 379nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153690(US9000015, 7 | US9610299, Example 7 | US10507215, ...)
Affinity DataIC50: 464nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153691(US9000015, 8 | US9610299, Example 8 | US10507215, ...)
Affinity DataIC50: 480nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
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TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153693(US9000015, 10 | US9610299, Example 10 | US10507215...)
Affinity DataIC50: 890nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153689(US9000015, 6 | US10507215, Compound 6)
Affinity DataIC50: 1.11E+3nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153692(US9000015, 9 | US9610299, Example 9 | US10507215, ...)
Affinity DataIC50: 2.09E+3nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAldehyde dehydrogenase, mitochondrial(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153697(US9000015, 14 | US9610299, Example 14 | US10507215...)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153697(US9000015, 14 | US9610299, Example 14 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
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TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153696(US9000015, 13 | US9610299, Example 13 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153695(US9000015, 12 | US9610299, Example 12 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153694(US9000015, 11 | US9610299, Example 11 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153693(US9000015, 10 | US9610299, Example 10 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153692(US9000015, 9 | US9610299, Example 9 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153691(US9000015, 8 | US9610299, Example 8 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153690(US9000015, 7 | US9610299, Example 7 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153689(US9000015, 6 | US10507215, Compound 6)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153688(US9000015, 5 | US10507215, Compound 5)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153687(US9000015, 4 | US10507215, Compound 4)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153686(US9000015, 3 | US9610299, Example 3 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153685(US9000015, 2 | US9610299, Example 2 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153697(US9000015, 14 | US9610299, Example 14 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153684(US9000015, 1 | US9610299, Example 1 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153696(US9000015, 13 | US9610299, Example 13 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153695(US9000015, 12 | US9610299, Example 12 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153694(US9000015, 11 | US9610299, Example 11 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153693(US9000015, 10 | US9610299, Example 10 | US10507215...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153692(US9000015, 9 | US9610299, Example 9 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153691(US9000015, 8 | US9610299, Example 8 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153690(US9000015, 7 | US9610299, Example 7 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153689(US9000015, 6 | US10507215, Compound 6)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153688(US9000015, 5 | US10507215, Compound 5)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153687(US9000015, 4 | US10507215, Compound 4)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153686(US9000015, 3 | US9610299, Example 3 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153685(US9000015, 2 | US9610299, Example 2 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Gilead Sciences

US Patent
LigandPNGBDBM153684(US9000015, 1 | US9610299, Example 1 | US10507215, ...)
Affinity DataIC50: 1.30E+5nMpH: 7.5Assay Description:MAO assays included luminogenic MAO substrate, reaction buffers, Luciferin Detection and the reconstitution buffer with eserase. Standard MAO reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent