Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 6759
TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151177(US8987287, 7 | BDBM151178)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
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Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151177(US8987287, 7 | BDBM151178)
Affinity DataKi:  0.230nM ΔG°:  -55.0kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
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Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151184(US8987287, 63)
Affinity DataKi:  0.300nM ΔG°:  -54.4kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
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Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151183(US8987287, 49)
Affinity DataKi:  0.470nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
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Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151173(US8987287, 3)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151184(US8987287, 63)
Affinity DataKi:  0.860nM ΔG°:  -56.1kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
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Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151175(US8987287, 5)
Affinity DataKi:  0.940nM ΔG°:  -51.5kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151183(US8987287, 49)
Affinity DataKi:  2.28nM ΔG°:  -53.5kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
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Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151175(US8987287, 5)
Affinity DataKi:  3.55nM ΔG°:  -52.3kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
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Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151177(US8987287, 7 | BDBM151178)
Affinity DataKi:  8.39nM ΔG°:  -50.0kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151176(US8987287, 6)
Affinity DataKi:  12.3nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151173(US8987287, 3)
Affinity DataKi:  15.9nM ΔG°:  -48.2kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
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Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151180(US8987287, 10)
Affinity DataKi:  27.0nM ΔG°:  -46.8kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
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Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151172(US8987287, 2)
Affinity DataKi:  130nM ΔG°:  -39.3kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151174(US8987287, 4)
Affinity DataKi:  135nM ΔG°:  -39.2kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151180(US8987287, 10)
Affinity DataKi:  155nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetDelta-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151173(US8987287, 3)
Affinity DataKi:  177nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:Delta-Opioid Receptor Binding Assay Procedures: delta-Opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displaceme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetDelta-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151175(US8987287, 5)
Affinity DataKi:  272nM ΔG°:  -37.5kJ/molepH: 7.4 T: 2°CAssay Description:Delta-Opioid Receptor Binding Assay Procedures: delta-Opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displaceme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151179(US8987287, 9)
Affinity DataKi:  3.88E+3nM ΔG°:  -33.5kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151172(US8987287, 2)
Affinity DataKi:  9.05E+3nM ΔG°:  -31.2kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151182(US8987287, 12)
Affinity DataKi:  1.49E+4nM ΔG°:  -29.9kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151179(US8987287, 9)
Affinity DataKi: >2.00E+4nM ΔG°: >-26.8kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151181(US8987287, 11)
Affinity DataKi: >2.00E+4nM ΔG°: >-26.8kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151182(US8987287, 12)
Affinity DataKi: >2.00E+4nM ΔG°: >-26.8kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 ug membrane protein (recombinant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
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TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM151181(US8987287, 11)
Affinity DataKi: >2.00E+4nM ΔG°: >-29.1kJ/molepH: 7.4 T: 2°CAssay Description:mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
Go to US Patent