Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 6689
TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147165(US8957083, 39)
Affinity DataIC50: 0.200nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147160(US8957083, 34)
Affinity DataIC50: 0.300nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147154(US8957083, 32 | US8957083, 30)
Affinity DataIC50: 0.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147184(US8957083, 26)
Affinity DataIC50: 0.600nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147185(US8957083, 27)
Affinity DataIC50: 0.700nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147150(US8957083, 9)
Affinity DataIC50: 0.900nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147154(US8957083, 32 | US8957083, 30)
Affinity DataIC50: 0.900nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147178(US8957083, 19)
Affinity DataIC50: 1.40nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147175(US8957083, 16)
Affinity DataIC50: 1.40nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147186(US8957083, 28)
Affinity DataIC50: 2nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147174(US8957083, 18)
Affinity DataIC50: 2.40nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147182(US8957083, 17)
Affinity DataIC50: 2.80nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147159(US8957083, 37)
Affinity DataIC50: 2.90nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147158(US8957083, 36 | US8957083, 33)
Affinity DataIC50: 4.10nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147187(US8957083, 40)
Affinity DataIC50: 6.70nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147168(US8957083, 22)
Affinity DataIC50: 9.30nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147169(US8957083, 24)
Affinity DataIC50: 12.1nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147173(US8957083, 21- B)
Affinity DataIC50: 12.2nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147148(US8957083, 8)
Affinity DataIC50: 13.4nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147152(US8957083, 29)
Affinity DataIC50: 13.6nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147183(US8957083, 13)
Affinity DataIC50: 22.8nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147161(US8957083, 35)
Affinity DataIC50: 24.3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147177(US8957083, 15)
Affinity DataIC50: 33.2nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147179(US8957083, 21)
Affinity DataIC50: 48.3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147164(US8957083, 38)
Affinity DataIC50: 169nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147155(US8957083, 31)
Affinity DataIC50: 179nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147158(US8957083, 36 | US8957083, 33)
Affinity DataIC50: 225nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147172(US8957083, 21- A)
Affinity DataIC50: 437nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147170(US8957083, 23)
Affinity DataIC50: 1.75E+3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147171(US8957083, 25)
Affinity DataIC50: 2.43E+3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
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Date in BDB:
7/10/2015
Entry Details
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TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM147176(US8957083, 14)
Affinity DataIC50: 8.21E+3nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
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