Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 6587
TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140253(US8906911, 62)
Affinity DataIC50: 445nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140200(US8906911, 9)
Affinity DataIC50: 470nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140248(US8906911, 57)
Affinity DataIC50: 521nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140233(US8906911, 42)
Affinity DataIC50: 812nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140212(US8906911, 21)
Affinity DataIC50: 821nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140250(US8906911, 59)
Affinity DataIC50: 830nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140222(US8906911, 31)
Affinity DataIC50: 1.02E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140214(US8906911, 23)
Affinity DataIC50: 1.11E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140208(US8906911, 17)
Affinity DataIC50: 1.29E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140215(US8906911, 24)
Affinity DataIC50: 1.39E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140246(US8906911, 55)
Affinity DataIC50: 1.41E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140202(US8906911, 11)
Affinity DataIC50: 1.47E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140234(US8906911, 43)
Affinity DataIC50: 1.52E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140201(US8906911, 10)
Affinity DataIC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140235(US8906911, 44)
Affinity DataIC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140228(US8906911, 37)
Affinity DataIC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140229(US8906911, 38)
Affinity DataIC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140236(US8906911, 45)
Affinity DataIC50: 2.20E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140194(US8906911, 3)
Affinity DataIC50: 2.50E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140225(US8906911, 34)
Affinity DataIC50: 2.78E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140226(US8906911, 35)
Affinity DataIC50: 2.78E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140245(US8906911, 54)
Affinity DataIC50: 2.78E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140249(US8906911, 58)
Affinity DataIC50: 2.78E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140199(US8906911, 8)
Affinity DataIC50: 1.44E+4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140224(US8906911, 33)
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140195(US8906911, 4)
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140232(US8906911, 41)
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140259(US8906911, Compound B)
Affinity DataIC50: 2.80E+4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140258(US8906911, Compound A)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140256(US8906911, 65)
Affinity DataKi:  6nM ΔG°:  -43.6kJ/mole IC50: 28nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140239(US8906911, 48)
Affinity DataKi:  8nM ΔG°:  -43.0kJ/mole IC50: 51.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140254(US8906911, 63)
Affinity DataKi:  10nM ΔG°:  -42.4kJ/mole IC50: 17.9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140255(US8906911, 64)
Affinity DataKi:  12nM ΔG°:  -42.0kJ/mole IC50: 16.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140257(US8906911, 66)
Affinity DataKi:  13nM ΔG°:  -41.8kJ/mole IC50: 45.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140240(US8906911, 49)
Affinity DataKi:  15nM ΔG°:  -41.5kJ/mole IC50: 37nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140244(US8906911, 53)
Affinity DataKi:  16nM ΔG°:  -41.4kJ/mole IC50: 47.9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140237(US8906911, 46)
Affinity DataKi:  17nM ΔG°:  -41.2kJ/mole IC50: 17.6nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140242(US8906911, 51)
Affinity DataKi:  21nM ΔG°:  -40.7kJ/mole IC50: 43.3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140197(US8906911, 6)
Affinity DataKi:  28nM ΔG°:  -40.1kJ/mole IC50: 32.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140206(US8906911, 15)
Affinity DataKi:  29nM ΔG°:  -40.0kJ/mole IC50: 34.7nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140198(US8906911, 7)
Affinity DataKi:  30nM ΔG°:  -39.9kJ/mole IC50: 65.7nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140205(US8906911, 14)
Affinity DataKi:  31nM ΔG°:  -39.8kJ/mole IC50: 43nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140219(US8906911, 28)
Affinity DataKi:  32nM ΔG°:  -39.8kJ/mole IC50: 19.8nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140247(US8906911, 56)
Affinity DataKi:  32nM ΔG°:  -39.8kJ/mole IC50: 46nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140192(US8906911, 1)
Affinity DataKi:  32nM ΔG°:  -39.8kJ/mole IC50: 54.9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140231(US8906911, 40)
Affinity DataKi:  38nM ΔG°:  -39.4kJ/mole IC50: 41.5nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140243(US8906911, 52)
Affinity DataKi:  49nM ΔG°:  -38.8kJ/mole IC50: 83.9nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140193(US8906911, 2)
Affinity DataKi:  60nM ΔG°:  -38.3kJ/mole IC50: 76.7nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140230(US8906911, 39)
Affinity DataKi:  66nM ΔG°:  -38.1kJ/mole IC50: 55.3nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140252(US8906911, 61)
Affinity DataKi:  69nM ΔG°:  -38.0kJ/mole IC50: 100nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
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