Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 6536
TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM136702(US8865655, 10)
Affinity DataIC50: 4.40nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
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TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM136703(US8865655, 11)
Affinity DataIC50: 21.6nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM136704(US8865655, 16)
Affinity DataIC50: 47nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM136705(US8865655, 17)
Affinity DataIC50: 126nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
Go to US Patent