Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 6427
TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM50307959(US8796293, 54 | CHEMBL596991 | 4-(4-Chlorobenzyl)-...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
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TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM128294(US8796293, 30)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
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TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM50307955(CHEMBL597414 | US8796293, 59 | 4-(2,4-Dichlorobenz...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
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TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM128293(US8796293, 14)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
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TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM50307942(CHEMBL598194 | US8796293, 69 | 4-Amino-N-(4-chloro...)
Affinity DataIC50: 143nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM128292(US8796293, 4)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
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TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM50237622(US8796293, 17 | 4-(4-Chlorobenzyl)-1-(7H-pyrrolo[2...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
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TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM50307981(US8796293, 55 | CHEMBL598439 | 4-(2-Chlorobenzyl)-...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
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TargetRho-associated protein kinase 2(Human)
The Institute of Cancer Research

US Patent
LigandPNGBDBM50307943(US8796293, 56 | CHEMBL597211 | 4-(4-tert-Butylbenz...)
Affinity DataIC50: 2.70E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 ul, ROCK-II (h) (5-10 mU) is incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 uM KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
Go to US Patent