Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 6400
TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364687(CHEMBL1951476 | US8785634, 8)
Affinity DataIC50: 0.490nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
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TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364676(CHEMBL1951465 | US8785634, 1)
Affinity DataIC50: 0.660nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364679(CHEMBL1951468 | US8785634, 2)
Affinity DataIC50: 1.30nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364682(CHEMBL1951471 | US8785634, 82)
Affinity DataIC50: 1.60nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364672(CHEMBL1951461 | US8785634, 3)
Affinity DataIC50: 5.20nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM126716(US8785634, 86)
Affinity DataIC50: 7.80nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM126715(US8785634, 21)
Affinity DataIC50: 65nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM126713(US8785634, 9)
Affinity DataIC50: 89nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM126714(US8785634, 69)
Affinity DataIC50: 235nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent