Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 6255
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119725(US8680132, MI- 519- 6401 | US9079913, MI-519-6401)
Affinity DataIC50: 5.60nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119736(US8680132, C09101 | US9079913, C091)
Affinity DataIC50: 8nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119726(US8680132, MI- 77301 (TFA salt) | US8680132, MI- 7...)
Affinity DataIC50: 8.20nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119743(US8680132, C09701)
Affinity DataIC50: 11nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119737(US8680132, C09601 | US9079913, C096)
Affinity DataIC50: 12nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119726(US8680132, MI- 77301 (TFA salt) | US8680132, MI- 7...)
Affinity DataIC50: 13.3nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119732(US8680132, C03401 | US9079913, C03401)
Affinity DataIC50: 18nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119741(US8680132, MI- 710601 | US9079913, MI-710601)
Affinity DataIC50: 20.1nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119729(US8680132, C02701 | US9079913, C02701)
Affinity DataIC50: 27nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119742(US8680132, MI- 710801)
Affinity DataIC50: 32nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119730(US8680132, C02901 | US9079913, C02901)
Affinity DataIC50: 35nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119711(US8680132, MI- 519-64 | US9079913, MI-519-64)
Affinity DataIC50: 41.4nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119718(US8680132, C034 | US9079913, C034)
Affinity DataIC50: 48nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119733(US8680132, C03701 | US9079913, C03701)
Affinity DataIC50: 61nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119738(US8680132, MI- 710201 | US9079913, MI-710201)
Affinity DataIC50: 61.7nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119713(US8680132, MI- 773 | US9079913, MI-773)
Affinity DataIC50: 62.1nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119740(US8680132, MI- 710401 | US9079913, MI-710401)
Affinity DataIC50: 70.2nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119732(US8680132, C03401 | US9079913, C03401)
Affinity DataIC50: 85.6nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119731(US8680132, C03001 | US9079913, C03001)
Affinity DataIC50: 89.6nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119731(US8680132, C03001 | US9079913, C03001)
Affinity DataIC50: 100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119734(US8680132, C08301 | US9079913, C08301)
Affinity DataIC50: 100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119745(US8680132, CB061- Isomer B)
Affinity DataIC50: 100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119750(US8680132, C30201)
Affinity DataIC50: 100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119749(US8680132, C29701)
Affinity DataIC50: 100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119710(US8680132, MI- 21901)
Affinity DataIC50: 104nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119732(US8680132, C03401 | US9079913, C03401)
Affinity DataIC50: 108nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119729(US8680132, C02701 | US9079913, C02701)
Affinity DataIC50: 112nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119731(US8680132, C03001 | US9079913, C03001)
Affinity DataIC50: 120nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119730(US8680132, C02901 | US9079913, C02901)
Affinity DataIC50: 122nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119740(US8680132, MI- 710401 | US9079913, MI-710401)
Affinity DataIC50: 138nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119729(US8680132, C02701 | US9079913, C02701)
Affinity DataIC50: 149nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119740(US8680132, MI- 710401 | US9079913, MI-710401)
Affinity DataIC50: 158nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119744(US8680132, C11701)
Affinity DataIC50: 159nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119730(US8680132, C02901 | US9079913, C02901)
Affinity DataIC50: 160nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119735(US8680132, C08601 | US9079913, C08601)
Affinity DataIC50: 162nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119715(US8680132, C027 | US9079913, C027)
Affinity DataIC50: 167nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119722(US8680132, MI- 7104)
Affinity DataIC50: 169nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119721(US8680132, MI- 7102 | US9079913, MI-7102)
Affinity DataIC50: 175nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119716(US8680132, C029 | US9079913, MI-7105)
Affinity DataIC50: 176nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM50300121(US8680132, MI- 219 | CHEMBL572933 | (2'R,3S,4'R,5'...)
Affinity DataIC50: 180nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119742(US8680132, MI- 710801)
Affinity DataIC50: 185nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119733(US8680132, C03701 | US9079913, C03701)
Affinity DataIC50: 220nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119742(US8680132, MI- 710801)
Affinity DataIC50: 225nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119741(US8680132, MI- 710601 | US9079913, MI-710601)
Affinity DataIC50: 256nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119739(US8680132, MI- 710301 | US9079913, MI-710301)
Affinity DataIC50: 260nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119733(US8680132, C03701 | US9079913, C03701)
Affinity DataIC50: 270nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119738(US8680132, MI- 710201 | US9079913, MI-710201)
Affinity DataIC50: 273nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119741(US8680132, MI- 710601 | US9079913, MI-710601)
Affinity DataIC50: 290nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119738(US8680132, MI- 710201 | US9079913, MI-710201)
Affinity DataIC50: 308nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandPNGBDBM119739(US8680132, MI- 710301 | US9079913, MI-710301)
Affinity DataIC50: 309nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
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