Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 6240
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119227(US8673938, 162)
Affinity DataIC50: 6nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119220(US8673938, 91)
Affinity DataIC50: 6nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119215(US8673938, 68)
Affinity DataIC50: 6nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119216(US8673938, 74)
Affinity DataIC50: 6nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119217(US8673938, 75)
Affinity DataIC50: 6nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM50392216(CHEMBL2153191 | US8673938, 7)
Affinity DataIC50: 7nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119221(US8673938, 99)
Affinity DataIC50: 7nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119214(US8673938, 60)
Affinity DataIC50: 8nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119219(US8673938, 81)
Affinity DataIC50: 9nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119218(US8673938, 78)
Affinity DataIC50: 9nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119222(US8673938, 112)
Affinity DataIC50: 16nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119228(US8673938, 177)
Affinity DataIC50: 20nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119212(US8673938, 42)
Affinity DataIC50: 21nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119224(US8673938, 121)
Affinity DataIC50: 31nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119213(US8673938, 54)
Affinity DataIC50: 35nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119226(US8673938, 158)
Affinity DataIC50: 79nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM50392234(CHEMBL2153190 | US8673938, 1)
Affinity DataIC50: 95nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119223(US8673938, 117)
Affinity DataIC50: 100nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119225(US8673938, 136)
Affinity DataIC50: 120nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119209(US8673938, 6)
Affinity DataIC50: 157nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM50392235(CHEMBL2153192 | US8673938, 4)
Affinity DataIC50: 198nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119211(US8673938, 30)
Affinity DataIC50: 240nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM119210(US8673938, 25)
Affinity DataIC50: 250nMAssay Description:The conversion of cortisone to the active steroid cortisol by 11βHSD1 oxo-reductase activity, can be measured using a competitive homogeneous ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2014
Entry Details
Go to US Patent