Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 6095
TargetSerine/threonine-protein kinase PLK1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataIC50: 8nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataIC50: 30nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM108214(US8598172, 1)
Affinity DataIC50: 32nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataIC50: 90nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM108214(US8598172, 1)
Affinity DataIC50: 1.13E+3nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM108214(US8598172, 1)
Affinity DataIC50: 1.29E+3nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent