Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 6060
TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106943(US8592468, EbSe10 | acs.jmedchem.1c00409_ST.159)
Affinity DataIC50: 1.50E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
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TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106945(US8592468, EbSe3)
Affinity DataIC50: 1.50E+4nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
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TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106946(US8592468, EbSe4)
Affinity DataIC50: 1.50E+4nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106947(US8592468, EbSe11)
Affinity DataIC50: 4.00E+4nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
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TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM50385299(CHEMBL2035464 | US8592468, EbSe16)
Affinity DataKi:  10nM IC50: 2.25E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM50385302(CHEMBL2035461 | US8592468, EbSe15)
Affinity DataKi:  40nM IC50: 2.10E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
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TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM50385303(CHEMBL2035460 | US8592468, EbSe14)
Affinity DataKi:  50nM IC50: 2.00E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106948(US8592468, EbSe12)
Affinity DataKi:  250nM IC50: 3.00E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106941(US8592468, EbSe8)
Affinity DataKi:  250nM IC50: 6.00E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
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TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM34233(EBSELEN | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...)
Affinity DataKi:  300nM IC50: 6.00E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106940(US8592468, EbSe7)
Affinity DataKi:  550nM IC50: 7.00E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106944(US8592468, EbSe2)
Affinity DataKi:  1.00E+3nM IC50: 1.50E+4nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106942(US8592468, EbSe9)
Affinity DataKi:  1.20E+3nM IC50: 7.50E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106949(US8592468, EbSe13)
Affinity DataKi:  1.50E+3nM IC50: 3.00E+3nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent