Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 6048
TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50223567(US8580782, 8 | CHEMBL401303 | 3-bromo-5-(2-chlorop...)
Affinity DataIC50: 3nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105239(US8580782, 7)
Affinity DataIC50: 6nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105239(US8580782, 7)
Affinity DataIC50: 10nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105236(US8580782, 4)
Affinity DataIC50: 11nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105234(US8580782, 1)
Affinity DataIC50: 20nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105237(US8580782, 5 | US8575203, I-4)
Affinity DataIC50: 21nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105235(US8580782, 3)
Affinity DataIC50: 24nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105234(US8580782, 1)
Affinity DataIC50: 29nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105238(US8580782, 6 | US8575203, I-5)
Affinity DataIC50: 29nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105235(US8580782, 3)
Affinity DataIC50: 32nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105240(US8580782, 10)
Affinity DataIC50: 42nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105238(US8580782, 6 | US8575203, I-5)
Affinity DataIC50: 64nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105244(US8580782, 18)
Affinity DataIC50: 140nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
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TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105241(US8580782, 12)
Affinity DataIC50: 170nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105242(US8580782, 16)
Affinity DataIC50: 620nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM105243(US8580782, 17)
Affinity DataIC50: 5.60E+3nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent