Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 6000
TargetProlyl endopeptidase FAP(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103917(US8562945, 253)
Affinity DataIC50: 20nMAssay Description:Compounds were tested for their ability to inhibit separase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetProlyl endopeptidase FAP(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103918(US8562945, 254)
Affinity DataIC50: 21nMAssay Description:Compounds were tested for their ability to inhibit separase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103909(JNK3 inhibitor 6 | US8562945, 242)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103908(JNK3 inhibitor 5 | US8562945, 241)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103911(JNK3 inhibitor 8 | US8562945, 246)
Affinity DataIC50: 42nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103915(US8562945, 250)
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103911(JNK3 inhibitor 8 | US8562945, 246)
Affinity DataIC50: 140nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103909(JNK3 inhibitor 6 | US8562945, 242)
Affinity DataIC50: 170nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103914(US8562945, 249)
Affinity DataIC50: 189nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103913(US8562945, 248)
Affinity DataIC50: 260nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103912(US8562945, 247)
Affinity DataIC50: 305nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103914(US8562945, 249)
Affinity DataIC50: 405nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103908(JNK3 inhibitor 5 | US8562945, 241)
Affinity DataIC50: 445nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetCarbonic anhydrase 9(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50: 564nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50: 652nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103915(US8562945, 250)
Affinity DataIC50: 669nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103913(US8562945, 248)
Affinity DataIC50: 770nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103912(US8562945, 247)
Affinity DataIC50: 2.16E+3nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetProlyl endopeptidase FAP(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103916(US8562945, 252)
Affinity DataIC50: 3.53E+3nMAssay Description:Compounds were tested for their ability to inhibit separase enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetDipeptidyl peptidase 4(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103917(US8562945, 253)
Affinity DataIC50: 1.24E+4nMAssay Description:Compounds were tested for their ability to inhibit DPPIV enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetDipeptidyl peptidase 4(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103916(US8562945, 252)
Affinity DataIC50: 1.96E+4nMAssay Description:Compounds were tested for their ability to inhibit DPPIV enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
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TargetDipeptidyl peptidase 4(Human)
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103918(US8562945, 254)
Affinity DataIC50: 2.54E+4nMAssay Description:Compounds were tested for their ability to inhibit DPPIV enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent