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Report error Found 292 Enz. Inhib. hit(s) with all data for entry = 5959
TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102699(US8541572, 363)
Affinity DataIC50: 96nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102903(US8541572, 569)
Affinity DataIC50: 268nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102896(US8541572, 562)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102897(US8541572, 563)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102777(US8541572, 2207)
Affinity DataKi:  0.0300nM IC50: 260nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102624(US8541572, 303)
Affinity DataKi:  0.0300nM IC50: 383nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102623(US8541572, 302)
Affinity DataKi:  0.0521nM IC50: 723nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102666(US8541572, 973)
Affinity DataKi:  0.0524nM IC50: 61nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102663(US8541572, 970)
Affinity DataKi:  0.0556nM IC50: 65nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102802(US8541572, 2234)
Affinity DataKi:  0.0600nM IC50: 678nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102680(US8541572, 987)
Affinity DataKi:  0.0627nM IC50: 75.4nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102845(US8541572, 927)
Affinity DataKi:  0.0630nM IC50: 151nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102664(US8541572, 971)
Affinity DataKi:  0.0651nM IC50: 80.3nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102840(US8541572, 922)
Affinity DataKi:  0.0720nM IC50: 92nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50332292(US8541572, 934 | CHEMBL1288000 | (R)-5-((4-(3-hydr...)
Affinity DataKi:  0.0740nM IC50: 117nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102698(US8541572, 1008)
Affinity DataKi:  0.0762nM IC50: 342nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102695(US8541572, 1002)
Affinity DataKi:  0.0770nM IC50: 119nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102694(US8541572, 1001)
Affinity DataKi:  0.0781nM IC50: 106nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102696(US8541572, 1003)
Affinity DataKi:  0.0826nM IC50: 124nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102855(US8541572, 943)
Affinity DataKi:  0.0830nM IC50: 65nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102852(US8541572, 936)
Affinity DataKi:  0.0930nM IC50: 72.4nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102843(US8541572, 925)
Affinity DataKi:  0.0930nM IC50: 74nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102679(US8541572, 986)
Affinity DataKi:  0.0973nM IC50: 87nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102669(CHEMBL1288726 | US8541572, 976)
Affinity DataKi:  0.0988nM IC50: 39.8nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102863(US8541572, 2257)
Affinity DataKi:  0.100nM IC50: 490nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102844(US8541572, 926)
Affinity DataKi:  0.110nM IC50: 76nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102873(US8541572, 2267)
Affinity DataKi:  0.110nM IC50: 134nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102747(US8541572, 1918)
Affinity DataKi:  0.110nM IC50: 936nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102681(US8541572, 988)
Affinity DataKi:  0.115nM IC50: 55.9nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102731(US8541572, 1902)
Affinity DataKi:  0.120nM IC50: 127nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102857(US8541572, 946)
Affinity DataKi:  0.120nM IC50: 154nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102858(US8541572, 951)
Affinity DataKi:  0.120nM IC50: 220nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102872(US8541572, 2266)
Affinity DataKi:  0.120nM IC50: 927nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102853(US8541572, 941)
Affinity DataKi:  0.130nM IC50: 100nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102730(US8541572, 1901)
Affinity DataKi:  0.130nM IC50: 113nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102846(US8541572, 928)
Affinity DataKi:  0.150nM IC50: 278nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102789(US8541572, 2220)
Affinity DataKi:  0.150nM IC50: 417nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102800(US8541572, 2233)
Affinity DataKi:  0.150nM IC50: 811nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102834(US8541572, 911)
Affinity DataKi:  0.160nM IC50: 20nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102835(US8541572, 912)
Affinity DataKi:  0.160nM IC50: 153nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102784(US8541572, 2215)
Affinity DataKi:  0.160nM IC50: 229nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102819(US8541572, 2252)
Affinity DataKi:  0.160nM IC50: 258nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102738(US8541572, 1909)
Affinity DataKi:  0.170nM IC50: 78nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102856(US8541572, 945)
Affinity DataKi:  0.170nM IC50: 86nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102806(US8541572, 2239)
Affinity DataKi:  0.170nM IC50: 188nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102829(US8541572, 906)
Affinity DataKi:  0.170nM IC50: 382nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102720(US8541572, 1311)
Affinity DataKi:  0.180nM IC50: 69nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102736(US8541572, 1907)
Affinity DataKi:  0.180nM IC50: 86nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102861(US8541572, 954)
Affinity DataKi:  0.180nM IC50: 87nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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TargetTumor necrosis factor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102839(US8541572, 916)
Affinity DataKi:  0.180nM IC50: 274nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
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