Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 5882
TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM50266418(CHEMBL456055 | US8492564, 17 | (2S,4aR,6aR,7R,9S,1...)
Affinity DataKi:  20nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM50266390(US8492564, 13 | CHEMBL458870 | (2S,4aR,6aR,7R,9S,1...)
Affinity DataKi:  38nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM98547(US8492564, 6)
Affinity DataKi:  41nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM98546(US8492564, 7)
Affinity DataKi:  55nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM50266417(CHEMBL457341 | US8492564, 16 | (2S,4aR,6aR,7R,9S,1...)
Affinity DataKi:  83nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM50266445(US8492564, 20 | CHEMBL456923 | (2S,4aR,6aR,7R,9S,1...)
Affinity DataKi:  109nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM50266419(CHEMBL456056 | US8492564, 18 | (2S,4aR,6aR,7R,9S,1...)
Affinity DataKi:  154nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM50266420(US8492564, 19 | CHEMBL456057 | (2S,4aR,6aR,7R,9S,1...)
Affinity DataKi:  196nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM50266388(US8492564, 10 | CHEMBL458869 | (2S,4aR,6aR,7R,9S,1...)
Affinity DataKi:  497nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
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Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM50266387(US8492564, 9 | CHEMBL456695 | (2S,4aR,6aR,7R,9S,10...)
Affinity DataKi:  498nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
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TargetKappa-type opioid receptor(Human)
The Mclean Hospital

US Patent
LigandPNGBDBM50266389(US8492564, 11 | CHEMBL514597 | (2S,4aR,6aR,7R,9S,1...)
Affinity DataKi:  555nMAssay Description:In vitro binding assay: The affinities of compounds for opioid receptors were determined by competitive inhibition of [3H]diprenorphine binding to ka...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
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