Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 12899
TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738719(2-((1R,5S,6R)-3-(5-cyano-6-((S)- 2-methylazetidine...)
Affinity DataIC50: 0.170nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738731(Preparation of 2-((1R,5S,6R)-3-(5-cyano-6-((S)-2-m...)
Affinity DataIC50: 0.390nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738730(Preparation of 2-((1R,5S,6R)-3-(5-cyano-6-((S)-2-m...)
Affinity DataIC50: 0.440nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM319582(US10174007, Example 1 | US10787438, Example 1 | US...)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738157(US20250145619, Example 38)
Affinity DataIC50: 7.29nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738740(2-(1-(7,7-difluoro-2-((S)-2- methylazetidine-1-yl)...)
Affinity DataIC50: 10.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM319585(US10174007, Example 4 | US10787438, Example 4 | US...)
Affinity DataIC50: 10.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738721((R)-2-((1R,5S,6R)-3-(5-cyano-6- ((S)-2-methylazeti...)
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738722(3-(1-(5-cyano-6-((S)-2-methylazetidine- 1-yl)-4-(t...)
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM50629383(CHEMBL5434549 | US20250145619, Example 36)
Affinity DataIC50: 13.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738728(Preparation of 3-((S)-1-(5-cyano-6-((S)-2-methylaz...)
Affinity DataIC50: 15.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738747(US20250145619, Example 40)
Affinity DataIC50: 17.3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM50629380(CHEMBL5430902 | US20250145619, Example 6)
Affinity DataIC50: 19.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738727(Preparation of (R)-2-((1R,5S,6R)-3-(5-cyano-6-((S)...)
Affinity DataIC50: 24.7nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738720((S)-2-(2-(5-cyano-6-(2-methylazetidine- 1-yl)-4-(t...)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738712(US20250145619, Example 1)
Affinity DataIC50: 27.9nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738749(US20250145619, Example 46)
Affinity DataIC50: 30.2nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738745(US20250145619, Example 37)
Affinity DataIC50: 33.3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738718(2-(5-cyano-6-((S)-2-methylazetidine- 1-yl)-4-(trif...)
Affinity DataIC50: 36nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738742((S)-2-(2-(7,7-difluoro-2-(2- methylazetidine-1-yl)...)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738734((S)-6-(7,7-difluoro-2-(2-methylazetidine- 1-yl)-6,...)
Affinity DataIC50: 42.9nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738733((S)-2-(1-(7,7-difluoro-2-(2-methylazetidine- 1-yl)...)
Affinity DataIC50: 47nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738741((S)-2-(1-(7,7-difluoro-2-(2- methylazetidine-1-yl)...)
Affinity DataIC50: 52.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738735(2-(7,7-difluoro-2-((S)-2-methylazetidine- 1-yl)-6,...)
Affinity DataIC50: 59nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738732(US20250145619, Example 24)
Affinity DataIC50: 78.3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738729(Preparation of 3-((S)-1-(5-cyano-6-((S)-2-methylaz...)
Affinity DataIC50: 81.2nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738726(Preparation of (R)-2-((1R,5S,6R)-3-(5-cyano-6-((S)...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738716(US20250145619, Example 5)
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738714((S)-7-(5-cyano-6-(2- methylazetidine-1-yl)-4- (tri...)
Affinity DataIC50: 115nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738739(2-(7,7-difluoro-2-((2S,3R)-3-hydroxy- 2-methylazet...)
Affinity DataIC50: 134nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738743(2-(5-(7,7-difluoro-2-((S)-2- methylazetidine-1-yl)...)
Affinity DataIC50: 142nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738713((S)-2-(5-cyano-6-(2- methylazetidine-1-yl)-4- (tri...)
Affinity DataIC50: 143nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738715((S)-6-(2,2-dioxa-2-thioxa-6- azaspiro[3.3]heptan-6...)
Affinity DataIC50: 198nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738723(US20250145619, Example 15)
Affinity DataIC50: 212nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738748(2-((R)-1-(5-((S)-2-methylazetidine- 1-yl)pyridino[...)
Affinity DataIC50: 3.94E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738724(US20250145619, Example 16)
Affinity DataIC50: 6.31E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738737(2-(7,7-difluoro-2-((2S,3R)-2- methyl-3-(methylamin...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738738(2-(7,7-difluoro-2-((2S,3R)-3- methoxy-2-methylazet...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738736(2-(2-((2S,3R)-3-acetamido-2- methylazetidine-1-yl)...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
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TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM738725(US20250145619, Example 17)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent