Compile Data Set for Download or QSAR
Report error Found 292 Enz. Inhib. hit(s) with all data for entry = 12880
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736895(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.270nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736893((R)-8-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1...)
Affinity DataKi:  0.390nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736908(4-(6-((1-(5-Chloropyridin-2-yl)-4-methyl-1H-1,2,3-...)
Affinity DataKi:  0.460nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736967(US20250136581, Example 137)
Affinity DataKi:  0.490nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736858(1-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.520nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737023((S)-8-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1...)
Affinity DataKi:  0.540nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737001(US20250136581, Example 173)
Affinity DataKi:  0.550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736916(US20250136581, Example 81)
Affinity DataKi:  0.560nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736852(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.580nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736919(7-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736917(US20250136581, Example 82)
Affinity DataKi:  0.630nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737033((S)-8-(5-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1...)
Affinity DataKi:  0.640nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736929(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.670nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737000(1-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.670nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737010(US20250136581, Example 182)
Affinity DataKi:  0.710nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736924(3-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,2,3...)
Affinity DataKi:  0.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737022((S)-8-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1...)
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736946(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736915(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-(hydroxymeth...)
Affinity DataKi:  0.820nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736905(2-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.840nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736849(7-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.890nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736853(1-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.890nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736906(2-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.900nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736847(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.910nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736945(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.930nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736846(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  0.960nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737013(4-(6-((4-(Difluoromethyl)-1-(4-(difluoromethyl)phe...)
Affinity DataKi:  0.960nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736848(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736966(US20250136581, Example 135)
Affinity DataKi:  1.05nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
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TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736999(1-(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H...)
Affinity DataKi:  1.07nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736995(4-(6-((1-(4-(Difluoromethyl)-2-fluorophenyl)-4-met...)
Affinity DataKi:  1.08nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736885(1-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736890(1-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736926(2-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736931(1-(Cyclopropylmethyl)-4-(6-((1-(4-(difluoromethyl)...)
Affinity DataKi:  1.11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736997(4-(5-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736925(2-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736935(1-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736947(1-(1-(Difluoromethyl)-1H-pyrazol-4-yl)-4-(6-((1-(4...)
Affinity DataKi:  1.17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736900(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737008(2-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737009((S)-8-(6-((4-Chloro-1-(4-(difluoromethyl)phenyl)-1...)
Affinity DataKi:  1.21nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736855((S)-2-(6-((1-(4-(difluoromethyl)phenyl)-4-methyl-1...)
Affinity DataKi:  1.24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736860(4-(6-[(1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736939(9-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736949(2-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.25nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM737005((3S,9aR)-8-(6-((1-(4-(Difluoromethyl)phenyl)-4-met...)
Affinity DataKi:  1.26nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736937(1-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736975(4-(3-(4-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl...)
Affinity DataKi:  1.27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Shanghai Simr Biotechnology

US Patent
LigandPNGBDBM736844(1-(6-((1-(4-(Difluoromethyl)phenyl)-4-methyl-1H-1,...)
Affinity DataKi:  1.28nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2025
Entry Details
Go to US Patent

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