Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 12860
TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734353(2-(5-methoxy-2-methylphenyl)-1-[(3S)- | US20250129...)
Affinity DataKi:  0.230nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734349(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.230nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734366(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734381((2R)-2-(3,5-dimethoxyphenyl)-1-[(3S)- | US20250129...)
Affinity DataKi:  0.280nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734383(1-[(3S)-3-({5-[5-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.290nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734339(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734341(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734380(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734343(2-fluoro-1-[(3S)-3-{[6-methyl-5-(1- | US2025012904...)
Affinity DataKi:  0.340nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734345(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.450nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734350((2R)-1-[(3S)-3-({5-[5-(difluoromethyl)-1- | US2025...)
Affinity DataKi:  0.460nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734338(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  0.460nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734355(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.480nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734360(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  0.490nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734362(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  0.490nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734351((2R)-2-(5-chloro-2-methoxypyridin-4- | US202501290...)
Affinity DataKi:  0.510nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734378(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  0.530nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM50617052(CHEMBL5411999 | US20250129048, Example 7)
Affinity DataKi:  0.770nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734389(2-[3-(difluoromethoxy)-5- | US20250129048, Example...)
Affinity DataKi:  0.770nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734347(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  0.830nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734374(2-(3,4-dichlorophenyl)-1-[(3S)-3-({5-[2- | US20250...)
Affinity DataKi:  0.880nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734329((2R)-2-(5-Chloro-2-methoxypyridin-4-yl)-1-[(3S)-3-...)
Affinity DataKi:  0.880nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734387((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)- | US20250...)
Affinity DataKi:  0.910nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734369(2-[2-(difluoromethoxy)-6- | US20250129048, Example...)
Affinity DataKi:  0.930nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734375((2,2-difluoro-1-phenylcyclopropyl)[(3S)- | US20250...)
Affinity DataKi:  0.950nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734333((2R)-1-[(3S)-3-({5-[5-(1,1-Difluoroethyl)-1-methyl...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734370(2-(3-methoxy-4-methylphenyl)-1-[(3S)- | US20250129...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734340((2R)-1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US2025...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734358(2-(4-chlorophenyl)-1-[(3S)-3-({5-[2- | US202501290...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734373(1-[(3S)-3-({5-[5-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734335((2R)-2-(5-Chloro-2-methoxypyridin-4-yl)-1-[(3S)-3-...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM50617053(CHEMBL5437282 | US20250129048, Example 2)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734337((2R)-1-[(3S)-3-({5-[1-Cyclopropyl-5-(difluoromethy...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734386((2R)-2-(5-fluoro-2-methoxypyridin-4-yl)- | US20250...)
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734385(1-[(3S)-3-({5-[5-(difluoromethyl)-1- | US202501290...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734364(2-(2-methoxy-5-methylpyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734357(2-(2-methoxy-5-methylpyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734334((2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-[(3S)-3-...)
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734332(1-[(3R)-2,2-Dimethyl-3-{[6-methyl-5-(1-methyl-1H-i...)
Affinity DataKi:  4.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734376(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  4.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734371(1-[(3S)-3-{[5-(1,5-dimethyl-1H-pyrazol- | US202501...)
Affinity DataKi:  5.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734367(1-[(3S)-3-{[5-(6,6-difluoro-6,7-dihydro- | US20250...)
Affinity DataKi:  6.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734342(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  7.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734359(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734382(1-[(3S)-3-({5-[5-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  54nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734379(1-[(3S)-3-({5-[2-(difluoromethyl)-1- | US202501290...)
Affinity DataKi:  62nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734361(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  88nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734356(2-(2-methoxy-5-methylpyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734346(1-[(3S)-3-({5-[2-(1,1-difluoroethyl)-1- | US202501...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Pfizer

US Patent
LigandPNGBDBM734377(2-(5-chloro-2-methoxypyridin-4-yl)-1- | US20250129...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

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