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Found
33
Enz. Inhib. hit(s) with all data for entry = 12858
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734323
(US20250129032, Example 31)
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Affinity Data
IC50: 1.06nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734315
((S)-5-(1-fluoro-3-hydroxy-7-((methylamino)methyl)-...)
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Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734322
(US20250129032, Example 30)
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Affinity Data
IC50: 2.28nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734302
(US20250129032, Example 10)
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Affinity Data
IC50: 5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734293
((R)-5-(7-(2-aminoethyl)-1-fluoro-3-hydroxy-6,7,8,9...)
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Affinity Data
IC50: 5.07nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734298
(US20250129032, Example 6)
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Affinity Data
IC50: 5.67nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734308
(US20250129032, Example 16)
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Affinity Data
IC50: 10.7nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734311
(US20250129032, Example 19)
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Affinity Data
IC50: 12.4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734312
(US20250129032, Example 20)
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Affinity Data
IC50: 12.7nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734306
(US20250129032, Example 14)
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Affinity Data
IC50: 13.6nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734296
(US20250129032, Example 4)
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Affinity Data
IC50: 14.9nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734295
(US20250129032, Example 3)
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Affinity Data
IC50: 16.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
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Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734297
(US20250129032, Example 5)
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Affinity Data
IC50: 17.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734318
(US20250129032, Example 26)
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Affinity Data
IC50: 19.8nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734304
(US20250129032, Example 12)
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Affinity Data
IC50: 19.8nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734325
(US20250129032, Example 33)
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Affinity Data
IC50: 21.1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734301
(US20250129032, Example 9)
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Affinity Data
IC50: 21.6nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734314
(US20250129032, Example 22)
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Affinity Data
IC50: 24.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734317
(5-(1-fluoro-3-hydroxy-8-(isopentylamino)-6,7,8,9-t...)
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Affinity Data
IC50: 25.9nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734320
(US20250129032, Example 28)
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Affinity Data
IC50: 39.9nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734324
(US20250129032, Example 32)
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Affinity Data
IC50: 46.9nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734300
(US20250129032, Example 8)
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Affinity Data
IC50: 47.3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734316
(US20250129032, Example 24)
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Affinity Data
IC50: 75nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734307
(US20250129032, Example 15)
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Affinity Data
IC50: 79.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734305
(US20250129032, Example 13)
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Affinity Data
IC50: 85.3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734309
(US20250129032, Example 17)
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Affinity Data
IC50: 93nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734321
(US20250129032, Example 29)
Copy SMILES
Copy InChI
Affinity Data
IC50: 109nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734303
(US20250129032, Example 11)
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Affinity Data
IC50: 149nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734294
(US20250129032, Example 2)
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Affinity Data
IC50: 176nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734319
(US20250129032, Example 27)
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Affinity Data
IC50: 215nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734313
(US20250129032, Example 21)
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Affinity Data
IC50: 374nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734299
(US20250129032, Example 7)
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Affinity Data
IC50: 444nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Receptor-type tyrosine-protein phosphatase N2
(Human)
Nerio Therapeutics
US Patent
Ligand
BDBM734310
(US20250129032, Example 18)
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Affinity Data
IC50: 879nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL