Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 12821
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 2.46nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 2.72nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 2.82nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 3nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 3.52nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 4.12nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 4.44nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 4.54nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 6.31nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 6.55nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 7.27nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 8.16nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 8.80nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 9.27nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 11.4nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 18.2nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 24.2nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 28.2nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Shandong New Time Pharmaceutical
US Patent
Shandong New Time Pharmaceutical
US Patent
Affinity DataIC50: 93.6nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair