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Found
28
Enz. Inhib. hit(s) with all data for entry = 12819
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM662984
(Synthesis of 2,6-dimethoxy-N-(4-methoxy-6-(pyridin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730788
(US20250122182, Example 45, WO2020/254946)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM663033
(Synthesis of N-(6-((1H-pyrazol-1-yl)methyl)-4-(flu...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM580748
(US11492346, Example 90 | US20250122182, Example 98...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PDB
Similars
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
PDB
3D Structure (crystal)
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730792
(US20250122182, Syn. Ex. 25)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730781
(US20250122182, Syn. Ex. 102)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730790
(US20250122182, Syn. Ex. 14)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730783
(US20250122182, Syn. Ex. 107)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM662998
(Synthesis of 2,6-dimethoxy-N-(4-(pyridin-2-yloxy)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730780
(US20250122182, Syn. Ex. 101)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730791
(US20250122182, Syn. Ex. 15)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730785
(US20250122182, Syn. Ex. 52)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730789
(US20250122182, Syn. Ex. 7)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730788
(US20250122182, Example 45, WO2020/254946)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM663033
(Synthesis of N-(6-((1H-pyrazol-1-yl)methyl)-4-(flu...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 25.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6A
(Human)
Isosterix
US Patent
Ligand
BDBM730786
(US20250122182, Syn. Ex. 50)
Copy SMILES
Copy InChI
Affinity Data
IC50: 34nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM580748
(US11492346, Example 90 | US20250122182, Example 98...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PDB
Similars
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM662998
(Synthesis of 2,6-dimethoxy-N-(4-(pyridin-2-yloxy)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 144nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM662984
(Synthesis of 2,6-dimethoxy-N-(4-methoxy-6-(pyridin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 332nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730789
(US20250122182, Syn. Ex. 7)
Copy SMILES
Copy InChI
Affinity Data
IC50: 571nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730792
(US20250122182, Syn. Ex. 25)
Copy SMILES
Copy InChI
Affinity Data
IC50: 722nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730790
(US20250122182, Syn. Ex. 14)
Copy SMILES
Copy InChI
Affinity Data
IC50: 878nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730791
(US20250122182, Syn. Ex. 15)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.03E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730783
(US20250122182, Syn. Ex. 107)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.63E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730786
(US20250122182, Syn. Ex. 50)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730780
(US20250122182, Syn. Ex. 101)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.49E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730781
(US20250122182, Syn. Ex. 102)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.53E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Histone acetyltransferase KAT6B
(Human)
Isosterix
US Patent
Ligand
BDBM730785
(US20250122182, Syn. Ex. 52)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.67E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL