Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
Report error
Found
21
Enz. Inhib. hit(s) with all data for entry = 12849
Target
Serine/threonine-protein kinase SIK3
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733641
(1-[6-[6-[(6-Methylpyridazin-3-yl)amino]imidazo[4,5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK2
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733641
(1-[6-[6-[(6-Methylpyridazin-3-yl)amino]imidazo[4,5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK3
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733639
(1-[3-(1-Hydroxyethyl)-6-[6-[(6-methylpyridazin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK2
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733639
(1-[3-(1-Hydroxyethyl)-6-[6-[(6-methylpyridazin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK3
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733644
(1-[2-[3-(difluoromethyl)-5-methyl-pyrazol-1-yl]-6-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK2
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733644
(1-[2-[3-(difluoromethyl)-5-methyl-pyrazol-1-yl]-6-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK2
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733640
(1-[3-(1-Hydroxyethyl)-6-[6-[(6-methyl-3-pyridyl)am...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK3
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733640
(1-[3-(1-Hydroxyethyl)-6-[6-[(6-methyl-3-pyridyl)am...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK2
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733636
(1-[3-Acetyl-6-[6-[(6-methylpyridazin-3-yl)amino]im...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 42nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK1
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733640
(1-[3-(1-Hydroxyethyl)-6-[6-[(6-methyl-3-pyridyl)am...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 78nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK3
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733636
(1-[3-Acetyl-6-[6-[(6-methylpyridazin-3-yl)amino]im...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 121nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK1
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733639
(1-[3-(1-Hydroxyethyl)-6-[6-[(6-methylpyridazin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 366nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK1
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733641
(1-[6-[6-[(6-Methylpyridazin-3-yl)amino]imidazo[4,5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 396nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK2
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733642
(1-[3-acetyl-6-[6-[methyl-(6-methylpyridazin-3-yl)a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 687nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK1
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733644
(1-[2-[3-(difluoromethyl)-5-methyl-pyrazol-1-yl]-6-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 879nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK3
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733642
(1-[3-acetyl-6-[6-[methyl-(6-methylpyridazin-3-yl)a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.06E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK2
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733643
(1-[3-Acetyl-6-[6-(3-methyl-6,7-dihydropyridazino[4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.54E+3nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK3
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733643
(1-[3-Acetyl-6-[6-(3-methyl-6,7-dihydropyridazino[4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.29E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK1
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733636
(1-[3-Acetyl-6-[6-[(6-methylpyridazin-3-yl)amino]im...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.52E+3nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK1
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733643
(1-[3-Acetyl-6-[6-(3-methyl-6,7-dihydropyridazino[4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.74E+4nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Serine/threonine-protein kinase SIK1
(Human)
Hoffmann-La Roche
US Patent
Ligand
BDBM733642
(1-[3-acetyl-6-[6-[methyl-(6-methylpyridazin-3-yl)a...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90E+4nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/23/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
BDBM733641
