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Found
125
Enz. Inhib. hit(s) with all data for entry = 12840
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM732856
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(4-methyl-3- ...)
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Affinity Data
IC50: 0.130nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
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Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716154
(6-(((1S,2S,4S)-4-(3-chloro-5- (trifluoromethyl)phe...)
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Affinity Data
IC50: 0.188nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
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Go to US Patent
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Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM732850
(6-(((1S,2S,4S)-4-(3,5- dichlorophenyl)-2-(dimethyl...)
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Affinity Data
IC50: 0.222nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716141
(6-(((1S,2S,4S)-4-(4-chloro-3- (trifluoromethyl)phe...)
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Affinity Data
IC50: 0.247nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716153
(6-(((1S,2S,4S)-2-(ethyl- (methyl)amino)-4-(3- (tri...)
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Affinity Data
IC50: 0.272nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716124
(5-chloro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-(1-...)
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Affinity Data
IC50: 0.281nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM732837
(6-(((1S,2S,4S)-4-(3,4-dichloro- phenyl)-2-(dimethy...)
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Affinity Data
IC50: 0.301nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716163
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(3-methyl-5- ...)
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Affinity Data
IC50: 0.351nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716123
(5-chloro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-pyr...)
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Affinity Data
IC50: 0.388nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716159
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(2-methyl-5- ...)
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Affinity Data
IC50: 0.404nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716143
(6-(((1S,2S,4S)-4-(2-chloro-5- (trifluoromethyl)phe...)
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Affinity Data
IC50: 0.409nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM715698
(N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-2- (dimethylam...)
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Affinity Data
IC50: 0.427nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
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Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716126
(5-fluoro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-(di...)
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Affinity Data
IC50: 0.427nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM732845
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(4-fluoro-3- ...)
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Affinity Data
IC50: 0.473nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716124
(5-chloro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-(1-...)
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Affinity Data
IC50: 0.493nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716160
(2-methyl-6-(((1S,2S,4S)-2- morpholino-4-(3-(triflu...)
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Affinity Data
IC50: 0.527nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM732808
(N-pyrimidin-4-yl-6-[[rac- (1S,2S,4S)-2-(dimethylam...)
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Affinity Data
IC50: 0.574nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716132
(5-chloro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-4-(3-...)
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Affinity Data
IC50: 0.574nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716140
(6-(((1S,2S,4S)-2-(cyclobutyl- (methyl)amino)-4-(3-...)
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Affinity Data
IC50: 0.597nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716122
(N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-2-pyrrolidin-1...)
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Affinity Data
IC50: 0.602nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716157
(6-(((1S,2S,4S)-4-(3-(difluoro- methoxy)phenyl)-2-(...)
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Affinity Data
IC50: 0.615nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716158
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(3-(trifluoro...)
Copy SMILES
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Affinity Data
IC50: 0.615nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716168
(6-(((1S,2S,4S)-2-(dimethy- lamino)-4-(3-((trifluor...)
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Affinity Data
IC50: 0.635nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716144
(6-(((1S,2S,4S)-4-(2,5-dichloro- phenyl)-2-(dimethy...)
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Affinity Data
IC50: 0.645nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716147
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(3-fluoro-5- ...)
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Affinity Data
IC50: 0.646nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716117
(N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-4-[4-chloro-3-...)
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Affinity Data
IC50: 0.660nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM732809
(N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-2-pyrrolidin-1...)
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Affinity Data
IC50: 0.664nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716133
(2-methyl-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-(di...)
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Affinity Data
IC50: 0.664nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716148
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(2-fluoro-5- ...)
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Affinity Data
IC50: 0.687nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716159
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(2-methyl-5- ...)
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Affinity Data
IC50: 0.695nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716147
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(3-fluoro-5- ...)
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Affinity Data
IC50: 0.720nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716148
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(2-fluoro-5- ...)
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Affinity Data
IC50: 0.720nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
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Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716149
(2-Chloro-6-(((1S,2S,4S)-2- (dimethylamino)-4-(2-fl...)
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Affinity Data
IC50: 0.720nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716153
(6-(((1S,2S,4S)-2-(ethyl- (methyl)amino)-4-(3- (tri...)
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Affinity Data
IC50: 0.75nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM715724
(5-chloro-N-pyrimidin-4-yl-6- [[rac-(1S,2S,4S)-2- (...)
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Affinity Data
IC50: 0.765nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716128
(2-methyl-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-(di...)
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Affinity Data
IC50: 0.765nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM715695
(N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-2- (dimethylam...)
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Affinity Data
IC50: 0.900nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
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Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716125
(5-bromo-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-(dim...)
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Affinity Data
IC50: 0.900nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716165
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(2-methyl-3- ...)
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Affinity Data
IC50: 0.909nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM732845
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(4-fluoro-3- ...)
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Affinity Data
IC50: 0.913nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716151
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(2-fluoro-3- ...)
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Affinity Data
IC50: 0.915nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716152
(6-(((1S,2S,4S)-2-(Diethy- lamino)-4-(3-(trifluoro-...)
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Affinity Data
IC50: 0.915nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716151
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(2-fluoro-3- ...)
Copy SMILES
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Affinity Data
IC50: 0.917nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
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Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716162
(6-(((1S,2S,4S)-4-(3-chloro- phenyl)-2-(dimethylami...)
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Affinity Data
IC50: 0.919nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
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Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716144
(6-(((1S,2S,4S)-4-(2,5-dichloro- phenyl)-2-(dimethy...)
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Affinity Data
IC50: 0.935nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
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Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716164
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(3-(2,2,2-tri...)
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Affinity Data
IC50: 0.942nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
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Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716123
(5-chloro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-pyr...)
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Affinity Data
IC50: 0.950nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716145
(5-chloro-N-(pyrimidin-4-yl)-6- (((1S,2S,4S)-2-(pyr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.955nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716156
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(6-(trifluoro...)
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Affinity Data
IC50: 0.985nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
Sodium channel protein type 9 subunit alpha
(Human)
Genentech
US Patent
Ligand
BDBM716158
(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(3-(trifluoro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.989nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
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