Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 12780
TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728167((2R,6S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728209(2-[(4-methoxyphenyl) methyl]-2-azaspiro[3.3] hepta...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728197(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4- di...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728195(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 4-(5...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728194(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-(5-...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728192(2-[(4-fluorophenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728191(2-[(4-chlorophenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728190(2-[(4-chlorophenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728189(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-(5-...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728188(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-[5-...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728185(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-2,5-d...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728184(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-(5-...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728183(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-(5-...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728181(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R)-4-[5- (c...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728179(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-[5-...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728166((2R,6S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728178(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6R)-4-[5-...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728175(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-(5-...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728174(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,5S)-4-[5-...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728180(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R)-4-[5-(et...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728169((2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728170((2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728196(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 2,6-...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728208(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-[5-...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728207(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5-...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728206(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5-...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728205(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5-...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728203(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-[5-...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728168((2R,5S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728171((2R)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- 4-[...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728172((2R)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- 4-[...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728193(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5,...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728182(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-(5-...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728177(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6R)-4-[5-...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728176(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R)-4-(5-met...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728211(2-[(2-methoxyphenyl) methyl]-2-azaspiro[3.3] hepta...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728210(2-[(4-methylphenyl) methyl]-2-azaspiro[3.3] heptan...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728186(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-2,6-d...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728187(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-2,6-d...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728204(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-{5-...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728173((2R,6S)-N-{2-benzyl-2- azaspiro[3.3]heptan-6-yl}- ...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728202(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 4-[5...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728201(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)-4-[5-...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728200(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 4-(5...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728199(2-benzyl-2-azaspiro [3.3]heptan-6-yl (2R,6S)- 4-(5...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM728198(2-benzyl-2-azaspiro [3.3]heptan-2-yl (2R,6S)- 4-(5...)
Affinity DataKi: >500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent