Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 12760
TargetTyrosine-protein kinase JAK1 [583-855](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726104([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726105([3a(4)Z,10R]-6,9,10,15-tetramethyl-3,8- dioxo-3,5,...)
Affinity DataKd:  46nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 Protein [521-781](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726105([3a(4)Z,10R]-6,9,10,15-tetramethyl-3,8- dioxo-3,5,...)
Affinity DataKd: >1.00E+3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726105([3a(4)Z,10R]-6,9,10,15-tetramethyl-3,8- dioxo-3,5,...)
Affinity DataKd: >1.00E+3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726105([3a(4)Z,10R]-6,9,10,15-tetramethyl-3,8- dioxo-3,5,...)
Affinity DataKd: >1.00E+3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726104([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  1nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726104([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 Protein [521-781](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726104([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726104([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726104([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  130nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726106([3a(4)Z,10R]-20-fluoro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726103([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  170nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726103([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 Protein [521-781](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726103([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726103([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726103([3a(4)Z,10R]-20-chloro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726102([3a(4)Z]-20-chloro-6,9,15-trimethyl- 10,11,13,15-t...)
Affinity DataKd:  0.510nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726102([3a(4)Z]-20-chloro-6,9,15-trimethyl- 10,11,13,15-t...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 Protein [521-781](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726102([3a(4)Z]-20-chloro-6,9,15-trimethyl- 10,11,13,15-t...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 Protein [521-781](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726107([3a(4)Z,10R]-20-chloro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726108([3a(4)Z,10R]-20-fluoro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  1nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726108([3a(4)Z,10R]-20-fluoro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 Protein [521-781](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726108([3a(4)Z,10R]-20-fluoro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726108([3a(4)Z,10R]-20-fluoro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726108([3a(4)Z,10R]-20-fluoro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd:  410nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726108([3a(4)Z,10R]-20-fluoro-6,9,10,15- tetramethyl-10,1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726107([3a(4)Z,10R]-20-chloro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd:  1.30nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726107([3a(4)Z,10R]-20-chloro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726102([3a(4)Z]-20-chloro-6,9,15-trimethyl- 10,11,13,15-t...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726107([3a(4)Z,10R]-20-chloro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726107([3a(4)Z,10R]-20-chloro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd:  120nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726107([3a(4)Z,10R]-20-chloro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726106([3a(4)Z,10R]-20-fluoro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd:  3.40nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726106([3a(4)Z,10R]-20-fluoro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 Protein [521-781](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726106([3a(4)Z,10R]-20-fluoro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd:  5.20E+3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726106([3a(4)Z,10R]-20-fluoro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726106([3a(4)Z,10R]-20-fluoro-6,9,10,15,16- pentamethyl-1...)
Affinity DataKd:  730nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726097([3a(4)Z]-6,9,15,16-tetramethyl- 10,11,13,15-tetrah...)
Affinity DataKd:  1.20nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726099([3a(4)Z,10R]-20-chloro-10,15-dimethyl- 10,11,13,15...)
Affinity DataKd:  29nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726099([3a(4)Z,10R]-20-chloro-10,15-dimethyl- 10,11,13,15...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726098([3a(4)Z,10R]-20-chloro-6,10,15- trimethyl-10,11,13...)
Affinity DataKd:  3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726098([3a(4)Z,10R]-20-chloro-6,10,15- trimethyl-10,11,13...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 Protein [521-781](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726098([3a(4)Z,10R]-20-chloro-6,10,15- trimethyl-10,11,13...)
Affinity DataKd:  7.70E+3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726098([3a(4)Z,10R]-20-chloro-6,10,15- trimethyl-10,11,13...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726098([3a(4)Z,10R]-20-chloro-6,10,15- trimethyl-10,11,13...)
Affinity DataKd:  120nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [583-855](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726098([3a(4)Z,10R]-20-chloro-6,10,15- trimethyl-10,11,13...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
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TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726099([3a(4)Z,10R]-20-chloro-10,15-dimethyl- 10,11,13,15...)
Affinity DataKd:  1.80E+3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726097([3a(4)Z]-6,9,15,16-tetramethyl- 10,11,13,15-tetrah...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
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TargetTyrosine-protein kinase JAK3 Protein [521-781](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726097([3a(4)Z]-6,9,15,16-tetramethyl- 10,11,13,15-tetrah...)
Affinity DataKd:  510nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
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TargetTyrosine-protein kinase JAK2 [536-812](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM726097([3a(4)Z]-6,9,15,16-tetramethyl- 10,11,13,15-tetrah...)
Affinity DataKd:  2.30E+3nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1× binding buffer (20% SeaBlock, 0.17×PBS, 0.05...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/10/2025
Entry Details
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