Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 12742
TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724637(US20250066377, Example 23)
Affinity DataIC50: 90nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724665(US20250066377, Example 51)
Affinity DataIC50: 100nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724649(US20250066377, Example 35)
Affinity DataIC50: 200nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724604(US20250066377, Example 03)
Affinity DataIC50: 200nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724651(US20250066377, Example 37)
Affinity DataIC50: 200nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724670(US20250066377, Example 56)
Affinity DataIC50: 200nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724668(US20250066377, Example 54)
Affinity DataIC50: 200nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724633(US20250066377, Example 19)
Affinity DataIC50: 300nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724627(US20250066377, Example 13)
Affinity DataIC50: 300nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724621(US20250066377, Example 07)
Affinity DataIC50: 400nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724664(US20250066377, Example 50)
Affinity DataIC50: 400nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724619(US20250066377, Example 05)
Affinity DataIC50: 400nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724628(US20250066377, Example 14)
Affinity DataIC50: 400nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724645(US20250066377, Example 31)
Affinity DataIC50: 400nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724654(US20250066377, Example 40)
Affinity DataIC50: 500nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724662(US20250066377, Example 48)
Affinity DataIC50: 500nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724631(US20250066377, Example 17)
Affinity DataIC50: 600nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724626(US20250066377, Example 12)
Affinity DataIC50: 900nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724644(US20250066377, Example 30)
Affinity DataIC50: 900nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724632(US20250066377, Example 18)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724650(US20250066377, Example 36)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724659(US20250066377, Example 45)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724667(US20250066377, Example 53)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724639(US20250066377, Example 25)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724602(US20250066377, Example 01)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724641(US20250066377, Example 27)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724642(US20250066377, Example 28)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724663(US20250066377, Example 49)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724652(US20250066377, Example 38)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724646(US20250066377, Example 32)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724653(US20250066377, Example 39)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724634(US20250066377, Example 20)
Affinity DataIC50: 2.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724660(US20250066377, Example 46)
Affinity DataIC50: 2.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724630(US20250066377, Example 16)
Affinity DataIC50: 2.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724629(US20250066377, Example 15)
Affinity DataIC50: 2.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724618(US20250066377, Example 04)
Affinity DataIC50: 2.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724603(US20250066377, Example 02)
Affinity DataIC50: 2.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724656(US20250066377, Example 42)
Affinity DataIC50: 3.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724636(US20250066377, Example 22)
Affinity DataIC50: 3.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724638(US20250066377, Example 24)
Affinity DataIC50: 3.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724635(US20250066377, Example 21)
Affinity DataIC50: 3.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724658(US20250066377, Example 44)
Affinity DataIC50: 5.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724671(US20250066377, Example 60)
Affinity DataIC50: 6.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724657(US20250066377, Example 43)
Affinity DataIC50: 7.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724655(US20250066377, Example 41)
Affinity DataIC50: 7.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724647(US20250066377, Example 33)
Affinity DataIC50: 7.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724643(US20250066377, Example 29)
Affinity DataIC50: 7.00E+3nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724666(US20250066377, Example 52)
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724669(US20250066377, Example 55)
Affinity DataIC50: 1.20E+4nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM724622(US20250066377, Example 08)
Affinity DataIC50: 1.80E+4nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

Displayed 1 to 50 (of 57 total ) | Next | Last >>
Jump to: