Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 12730
TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandPNGBDBM723998(US20250064791, Compound Rosiglitazone)
Affinity DataIC50: 2.00E+3nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2025
Entry Details
Go to US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandPNGBDBM50530214(CHEBI:82937 | Leriglitazone | Min-102 | US20240091...)
Affinity DataIC50: 4.10E+3nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2025
Entry Details
Go to US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandPNGBDBM723999(US20250064791, Compound UK5099)
Affinity DataIC50: 1.70E+4nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2025
Entry Details
Go to US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandPNGBDBM724000(US20250064791, Compound Pioglitazone)
Affinity DataIC50: 1.00E+5nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/29/2025
Entry Details
Go to US Patent