Compile Data Set for Download or QSAR
Report error Found 117 Enz. Inhib. hit(s) with all data for entry = 12714
TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 723354BDBM723354(US20250059185, Example 38)
Affinity DataIC50: 0.5nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722505BDBM722505(US20250059185, Example 107)
Affinity DataIC50: 0.610nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50625901BDBM50625901(CHEMBL5427191 | US20250059185, Example 29)
Affinity DataIC50: 1nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 723357BDBM723357(US20250059185, Example 49)
Affinity DataIC50: 1nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722503BDBM722503(US20250059185, Example 105)
Affinity DataIC50: 1.01nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722500BDBM722500(US20250059185, Example 102)
Affinity DataIC50: 1.53nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722486BDBM722486(US20250059185, Example 88)
Affinity DataIC50: 1.77nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722508BDBM722508(US20250059185, Example 110)
Affinity DataIC50: 2.09nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722511BDBM722511(US20250059185, Example 113)
Affinity DataIC50: 2.48nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50625902BDBM50625902(CHEMBL5432590 | US20250059185, Example 31)
Affinity DataIC50: 3nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722451BDBM722451(US20250059185, Example 53)
Affinity DataIC50: 3nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50625905BDBM50625905(CHEMBL5396984 | US20250059185, Example 69)
Affinity DataIC50: 3nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722490BDBM722490(US20250059185, Example 92)
Affinity DataIC50: 4.35nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722513BDBM722513(US20250059185, Example 115)
Affinity DataIC50: 4.88nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722435BDBM722435(US20250059185, Example 37)
Affinity DataIC50: 5nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 723358BDBM723358(US20250059185, Example 50)
Affinity DataIC50: 5nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722496BDBM722496(US20250059185, Example 98)
Affinity DataIC50: 5.97nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722482BDBM722482(US20250059185, Example 84)
Affinity DataIC50: 6.18nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722453BDBM722453(US20250059185, Example 55)
Affinity DataIC50: 7nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722485BDBM722485(US20250059185, Example 87)
Affinity DataIC50: 8.15nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722495BDBM722495(US20250059185, Example 97)
Affinity DataIC50: 8.44nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722454BDBM722454(US20250059185, Example 56)
Affinity DataIC50: 12nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722504BDBM722504(US20250059185, Example 106)
Affinity DataIC50: 12.4nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50625904BDBM50625904(CHEMBL5420101 | US20250059185, Example 64)
Affinity DataIC50: 13nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722483BDBM722483(US20250059185, Example 85)
Affinity DataIC50: 13.8nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722399BDBM722399(US20250059185, Example 1)
Affinity DataIC50: 14nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722493BDBM722493(US20250059185, Example 95)
Affinity DataIC50: 16.9nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50625899BDBM50625899(CHEMBL5407077 | US20250059185, Example 7)
Affinity DataIC50: 17nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722434BDBM722434(US20250059185, Example 36)
Affinity DataIC50: 17nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722479BDBM722479(US20250059185, Example 81)
Affinity DataIC50: 21nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722488BDBM722488(US20250059185, Example 90)
Affinity DataIC50: 24.6nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722440BDBM722440(US20250059185, Example 42)
Affinity DataIC50: 26nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722487BDBM722487(US20250059185, Example 89)
Affinity DataIC50: 26.8nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50625900BDBM50625900(CHEMBL5417048 | US20250059185, Example 23)
Affinity DataIC50: 27nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722418BDBM722418(US20250059185, Example 20)
Affinity DataIC50: 27nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722402BDBM722402(US20250059185, Example 4)
Affinity DataIC50: 27nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722498BDBM722498(US20250059185, Example 100)
Affinity DataIC50: 31.9nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722412BDBM722412(US20250059185, Example 14)
Affinity DataIC50: 41nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722417BDBM722417(US20250059185, Example 19)
Affinity DataIC50: 41nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722468BDBM722468(US20250059185, Example 70)
Affinity DataIC50: 42nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722502BDBM722502(US20250059185, Example 104)
Affinity DataIC50: 42.4nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722509BDBM722509(US20250059185, Example 111)
Affinity DataIC50: 51.6nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722439BDBM722439(US20250059185, Example 41)
Affinity DataIC50: 53nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722403BDBM722403(US20250059185, Example 5)
Affinity DataIC50: 59nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722470BDBM722470(US20250059185, Example 72)
Affinity DataIC50: 62nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 50625897BDBM50625897(CHEMBL5399772 | US20250059185, Example 3)
Affinity DataIC50: 63nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722420BDBM722420(US20250059185, Example 22)
Affinity DataIC50: 76nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722459BDBM722459(US20250059185, Example 61)
Affinity DataIC50: 77nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722424BDBM722424(US20250059185, Example 26)
Affinity DataIC50: 84nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 722404BDBM722404(US20250059185, Example 6)
Affinity DataIC50: 84nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

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