Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 12710
TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721524(US20250059156, Compound 224)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721489(US20250059156, Compound 115)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721490(US20250059156, Compound 103)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721491(US20250059156, Compound 102)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721518(US20250059156, Compound 218)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721511(US20250059156, Compound 120)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721507(US20250059156, Compound 209)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721521(US20250059156, Compound 221)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721503(US20250059156, Compound 117)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721502(US20250059156, Compound 118)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721499(US20250059156, Compound 110)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721500(US20250059156, Compound 111)
Affinity DataIC50: 50nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721501(US20250059156, Compound 208)
Affinity DataIC50: 75nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721517(US20250059156, Compound 216)
Affinity DataIC50: 75nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721516(US20250059156, Compound 215)
Affinity DataIC50: 75nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721509(US20250059156, Compound 203)
Affinity DataIC50: 75nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721498(US20250059156, Compound 109)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721515(US20250059156, Compound 214)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721519(US20250059156, Compound 219)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721512(US20250059156, Compound 121)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721493(US20250059156, Compound 104)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721510(US20250059156, Compound 204)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721494(US20250059156, Compound 105)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721508(US20250059156, Compound 210)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721520(US20250059156, Compound 220)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721497(US20250059156, Compound 108)
Affinity DataIC50: 300nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM50559715(CHEMBL4781238 | US20250059156, Compound Mesembreno...)
Affinity DataIC50: 470nMAssay Description:1) Dilute 20 μM FAM-Cyclic-3′, 5′-AMP stock 100-fold with PDE buffer to make a 200 nM solution. Make only sufficient quantity needed for the assay; s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721495(US20250059156, Compound 106)
Affinity DataIC50: 750nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721523(US20250059156, Compound 226)
Affinity DataIC50: 750nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721492(US20250059156, Compound 116)
Affinity DataIC50: 750nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721525(US20250059156, Compound 227)
Affinity DataIC50: 750nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721522(US20250059156, Compound 223)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721505(US20250059156, Compound 206)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721514(US20250059156, Compound 213)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721513(US20250059156, Compound 122)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721506(US20250059156, Compound 207)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721504(US20250059156, Compound 201)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM721496(US20250059156, Compound 107)
Affinity DataIC50: 1.00E+3nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM706753(mesembrine | US20240398759, Compound 001 | US20250...)
Affinity DataIC50: 7.80E+3nMAssay Description:1) Dilute 20 μM FAM-Cyclic-3′, 5′-AMP stock 100-fold with PDE buffer to make a 200 nM solution. Make only sufficient quantity needed for the assay; s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM706753(mesembrine | US20240398759, Compound 001 | US20250...)
Affinity DataKi:  1.40nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Sensorium Therapeutics

US Patent
LigandPNGBDBM50559715(CHEMBL4781238 | US20250059156, Compound Mesembreno...)
Affinity DataKi:  27nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HHH cells were prepared in a 384 microwell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent