Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 12684
TargetCoagulation factor XI(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM413849(US10421742, Example 242 | 4-{[(2S)-2-{4-[5-Chloro-...)
Affinity DataIC50: 0.890nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM413842(US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...)
Affinity DataIC50: 0.920nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPlasma kallikrein(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM413849(US10421742, Example 242 | 4-{[(2S)-2-{4-[5-Chloro-...)
Affinity DataIC50: 5.40nMAssay Description:In the thrombin generation assay according to Hemker, the activity of thrombin plasma is determined by measuring the fluorescent cleavage products of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPlasma kallikrein(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM413842(US10421742, Example 235 | 4-({(2S)-2-[4-{5-Chloro-...)
Affinity DataIC50: 5.70nMAssay Description:In the thrombin generation assay according to Hemker, the activity of thrombin plasma is determined by measuring the fluorescent cleavage products of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent