Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 12494
TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706716(US20240383924, Compound 018B)
Affinity DataIC50: 6.23nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706717(US20240383924, Compound 022)
Affinity DataIC50: 6.60nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706712(US20240383924, Compound 005)
Affinity DataIC50: 12.3nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706714(US20240383924, Compound 013B)
Affinity DataIC50: 15.9nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706715(US20240383924, Compound 017B)
Affinity DataIC50: 18.2nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706708(US20240383924, Compound 001B)
Affinity DataIC50: 18.9nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706711(US20240383924, Compound 003)
Affinity DataIC50: 20.4nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706709(US20240383924, Compound 002)
Affinity DataIC50: 22.5nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706710(US20240383924, Compound 002A)
Affinity DataIC50: 23.7nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706713(US20240383924, Compound 006)
Affinity DataIC50: 37.4nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
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Date in BDB:
4/12/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706718(US20240383924, Compound 029)
Affinity DataIC50: 38.6nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
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