Compile Data Set for Download or QSAR
Report error Found 98 Enz. Inhib. hit(s) with all data for entry = 12445
TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703019(2-((5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro- l...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703048(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703037(US20240368078, Compound 54)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703028(US20240368078, Compound 45)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703022(2-((5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro- l...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703039(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703047(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703025(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703060(US20240368078, Compound 77)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703061(2-cyclopropyl-2- ((3S,5R)-5-(2,3- dichloro-6- hydr...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703018(2-((5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro- l...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703046(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703017(2-((5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro- l...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703016(2-((5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro- l...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703030(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703044(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703026(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 100nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703051(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703035(US20240368078, Compound 52)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703050(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703034(US20240368078, Compound 51)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703033(US20240368078, Compound 50)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703014(US20240368078, Compound 31)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703032(N-(((3R,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrr...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703052(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703036(US20240368078, Compound 53)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703049(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703038(2-((2R,4S)-4-((1H- pyrazol-3- yl)methyl)pyrrolidin...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703053(1-(3,3- bis(hydroxymethyl) azetidin-1-yl)-2- ((3S,...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703040(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703041(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703042(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703043(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703045(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703031(US20240368078, Compound 48)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703020(2-((5R)-5-(2,3- dichloro-6- hdyroxyphenyl)pyrro- l...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703059(US20240368078, Compound 76)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703021(2-((5R)-5-(4,5- dichloro-2- hydroxyphenyl)pyrro- l...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703058(US20240368078, Compound 75)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703057(US20240368078, Compound 74)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703023(2-((5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro- l...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703062(2-cyclopropyl-2- ((3S,5R)-5-(2,3- dichloro-6- hydr...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703024(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703056(2-((3R,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703055(2-((3R,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703027(US20240368078, Compound 44)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703054(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703015(US20240368078, Compound 32)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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TargetPotassium voltage-gated channel subfamily A member 3(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703029(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:This assay is used to evaluate the disclosed compounds' activities as Kv1.3 potassium channel blockers. The cells were bathed in an extracellular...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
D.E. Shaw Research

US Patent
LigandPNGBDBM703042(2-((3S,5R)-5-(2,3- dichloro-6- hydroxyphenyl)pyrro...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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