Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 12378
TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM699298(US20240327433, Compound 7)
Affinity DataIC50: 0.100nMAssay Description:1) The concentration of a stock solution of the control compound was 1 mM, and the concentration of a stock solution of compounds to be assayed was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM699300(US20240327433, Compound 9)
Affinity DataIC50: 1.10nMAssay Description:1) The concentration of a stock solution of the control compound was 1 mM, and the concentration of a stock solution of compounds to be assayed was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM699293(US20240327433, Compound 1)
Affinity DataIC50: 2.5nMAssay Description:1) The concentration of a stock solution of the control compound was 1 mM, and the concentration of a stock solution of compounds to be assayed was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM699301(US20240327433, Compound 10)
Affinity DataIC50: 3.30nMAssay Description:1) The concentration of a stock solution of the control compound was 1 mM, and the concentration of a stock solution of compounds to be assayed was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM699296(US20240327433, Compound 5)
Affinity DataIC50: 12.7nMAssay Description:1) The concentration of a stock solution of the control compound was 1 mM, and the concentration of a stock solution of compounds to be assayed was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM699294(US20240327433, Compound 2)
Affinity DataIC50: 23nMAssay Description:1) The concentration of a stock solution of the control compound was 1 mM, and the concentration of a stock solution of compounds to be assayed was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM699297(US20240327433, Compound 6)
Affinity DataIC50: 30nMAssay Description:1) The concentration of a stock solution of the control compound was 1 mM, and the concentration of a stock solution of compounds to be assayed was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM699299(US20240327433, Compound 8)
Affinity DataIC50: 78.3nMAssay Description:1) The concentration of a stock solution of the control compound was 1 mM, and the concentration of a stock solution of compounds to be assayed was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
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TargetGTPase KRas [G12D](Human)
Medshine Discovery

US Patent
LigandPNGBDBM699295(US20240327433, Compound 3)
Affinity DataIC50: 425nMAssay Description:1) The concentration of a stock solution of the control compound was 1 mM, and the concentration of a stock solution of compounds to be assayed was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent