Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 12365
TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698769(US20240317745, Compound 47)
Affinity DataKi:  0.740nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5.04nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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PDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698774(US20240317745, Reference Compound 1)
Affinity DataKi:  6.17nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698767(US20240317745, Compound 43)
Affinity DataKi:  7.97nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698772(US20240317745, Compound 77)
Affinity DataKi:  14.9nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698768(US20240317745, Compound 44)
Affinity DataKi:  19nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698766(US20240317745, Compound 41)
Affinity DataKi:  34nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698770(US20240317745, Compound 65)
Affinity DataKi:  39.6nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698762(US20240317745, Compound 20)
Affinity DataKi:  48.9nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698760(US20240317745, Compound 1)
Affinity DataKi:  80.3nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698771(US20240317745, Compound 74)
Affinity DataKi:  84.4nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698761(US20240317745, Compound 19)
Affinity DataKi:  172nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698765(US20240317745, Compound 40)
Affinity DataKi:  190nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698763(US20240317745, Compound 37)
Affinity DataKi:  308nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698775(US20240317745, Reference Compound 2)
Affinity DataKi:  313nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698764(US20240317745, Compound 38)
Affinity DataKi:  378nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Humanwell Pharmaceutical US

US Patent
LigandPNGBDBM698773(US20240317745, Compound 88)
Affinity DataKi:  959nMAssay Description:An appropriate amount of homogenization buffer was added to the prepared membrane, and was dispersed into a suspension using a homogenizer, protein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent