Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 12358
TargetSodium-dependent serotonin transporter(Human)
Gilgamesh Pharmaceuticals

US Patent
LigandPNGBDBM693491(N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N- methylethan-...)
Affinity DataIC50: 419nMAssay Description:The ability of test compounds to block monoamine uptake by SERT was determined using the Neurotransmitter Transporter Uptake Assay Kit manufactured b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Gilgamesh Pharmaceuticals

US Patent
LigandPNGBDBM50578372(CHEMBL4871007 | US20240317683, Compound 1)
Affinity DataIC50: 750nMAssay Description:The ability of test compounds to block monoamine uptake by SERT was determined using the Neurotransmitter Transporter Uptake Assay Kit manufactured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Gilgamesh Pharmaceuticals

US Patent
LigandPNGBDBM50081701(4-hydroxy-N,N-dimethyltryptamine | N,N-dimethyl-4-...)
Affinity DataIC50: 2.04E+3nMAssay Description:The ability of test compounds to block monoamine uptake by SERT was determined using the Neurotransmitter Transporter Uptake Assay Kit manufactured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Gilgamesh Pharmaceuticals

US Patent
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...)
Affinity DataIC50: 2.96E+3nMAssay Description:The ability of test compounds to block monoamine uptake by SERT was determined using the Neurotransmitter Transporter Uptake Assay Kit manufactured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Gilgamesh Pharmaceuticals

US Patent
LigandPNGBDBM697970(US20240317683, Compound 6)
Affinity DataIC50: 3.27E+3nMAssay Description:The ability of test compounds to block monoamine uptake by SERT was determined using the Neurotransmitter Transporter Uptake Assay Kit manufactured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Gilgamesh Pharmaceuticals

US Patent
LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataIC50: 7.02E+3nMAssay Description:The ability of test compounds to block monoamine uptake by SERT was determined using the Neurotransmitter Transporter Uptake Assay Kit manufactured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Gilgamesh Pharmaceuticals

US Patent
LigandPNGBDBM697962(US20240317683, Compound 2)
Affinity DataIC50: 9.13E+3nMAssay Description:The ability of test compounds to block monoamine uptake by SERT was determined using the Neurotransmitter Transporter Uptake Assay Kit manufactured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2025
Entry Details
Go to US Patent