Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 12337
TargetNicotinamide phosphoribosyltransferase(Human)
University of Manchester

US Patent
LigandPNGBDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 1.60E+3nMAssay Description:In a 96-well opaque black plate, NAMPT (30 nM all concentrations provided as final), PRPP (50 μM) and ATP (2 mM) with or without test compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
University of Manchester

US Patent
LigandPNGBDBM696315(US20240300968, Example 1)
Affinity DataIC50: 5.11E+5nMAssay Description:In a 96-well opaque black plate, NAMPT (30 nM all concentrations provided as final), PRPP (50 μM) and ATP (2 mM) with or without test compounds ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
University of Manchester

US Patent
LigandPNGBDBM696316(US20240300968, Example 2)
Affinity DataIC50: 8.36E+6nMAssay Description:In a 96-well opaque black plate, NAMPT (30 nM all concentrations provided as final), PRPP (50 μM) and ATP (2 mM) with or without test compounds ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent