Compile Data Set for Download or QSAR
Report error Found 266 Enz. Inhib. hit(s) with all data for entry = 12273
TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593464(US11578066, Compound I-156 | N-(5-chloropyridin-3-...)
Affinity DataIC50: 2.53nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593418(US11578066, Compound I-109 | N-(5-chloropyridin-3-...)
Affinity DataIC50: 3.92nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593316(US11578066, Compound I-4 | N-(3-chlorophenyl)-N-((...)
Affinity DataIC50: 4.20nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593315(US11578066, Compound I-3 | N-(3-chlorophenyl-N-((5...)
Affinity DataIC50: 4.40nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593347(US11578066, Compound I-36 | N-(3-chlorophenyl)-N-(...)
Affinity DataIC50: 5nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593531(US11578066, Compound I-223 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 5.63nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593485(US11578066, Compound I-177 | N-[5-(difluoromethoxy...)
Affinity DataIC50: 6nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593533(US11578066, Compound I-225 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 6.01nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593523(US11578066, Compound I-215 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 6.75nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593465(US11578066, Compound I-157 | N-[5-(difluoromethoxy...)
Affinity DataIC50: 6.93nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593466(US11578066, Compound I-158 | N-(5-chloropyridin-3-...)
Affinity DataIC50: 7.22nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593346(US11578066, Compound I-35 | N-(4-(1H-imidazol-1-yl...)
Affinity DataIC50: 8nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593441(US11578066, Compound I-132 | N-[5-(2,2-difluoroeth...)
Affinity DataIC50: 9.64nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593467(US11578066, Compound I-159 | N-[5-(1,1-difluoroeth...)
Affinity DataIC50: 9.94nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593350(US11578066, Compound I-39 | N-(4-(1H-pyrazol-1-yl)...)
Affinity DataIC50: 10nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593405(US11578066, Compound I-96 | US11578066, Compound I...)
Affinity DataIC50: 10nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593406(US11578066, Compound I-97 | N-(6-cyanopyridin-3-yl...)
Affinity DataIC50: 10nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593488(US11578066, Compound I-180 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 10nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593421(US11578066, Compound I-112 | N-[5-(1,1-difluorethy...)
Affinity DataIC50: 10.1nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593454(US11578066, Compound I-145 | N-[5-(difluoromethoxy...)
Affinity DataIC50: 10.2nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593419(US11578066, Compound I-110 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 10.4nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593520(US11578066, Compound I-212 | (2S)-N-({5-[5-(difluo...)
Affinity DataIC50: 10.5nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593446(US11578066, Compound I-137 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 10.7nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593468(US11578066, Compound I-160 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 10.9nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593341(US11578066, Compound I-30 | N-((5-(5-(difluorometh...)
Affinity DataIC50: 11nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593524(US11578066, Compound I-216 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 11.9nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593327(US11578066, Compound I-16 | [(3-chlorophenyl)({5-[...)
Affinity DataIC50: 12nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593469(US11578066, Compound I-161 | N-(5-chloropyridin-3-...)
Affinity DataIC50: 12nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593535(US11578066, Compound I-227 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 12.3nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593499(US11578066, Compound I-191 | N-(5-chloropyridin-3-...)
Affinity DataIC50: 12.4nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593510(US11578066, Compound I-202 | N-(5-chloropyridin-3-...)
Affinity DataIC50: 12.7nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593348(US11578066, Compound I-37 | US20230381148, Compoun...)
Affinity DataIC50: 13nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593412(US11578066, Compound I-103 | N-((5-(5-(difluoromet...)
Affinity DataIC50: 13nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593440(US11578066, Compound I-131 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 13nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593445(US11578066, Compound I-136 | N-(5-cyclopropylpyrid...)
Affinity DataIC50: 13nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593487(US11578066, Compound I-179 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 13nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593576(US11578066, Compound I-268 | 3-[({5-[5-(difluorome...)
Affinity DataIC50: 13nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593515(US11578066, Compound I-207 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 13.7nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593519(US11578066, Compound I-211 | (2R)-N-({5-[5-(difluo...)
Affinity DataIC50: 13.7nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593417(US11578066, Compound I-108 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 13.8nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593325(US11578066, Compound I-14 | N-(3-chloro-4-fluoroph...)
Affinity DataIC50: 14nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593326(US11578066, Compound I-15 | N-((5-(5-(difluorometh...)
Affinity DataIC50: 14nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593401(US11578066, Compound I-92 | N-((5-(5-(difiuorometh...)
Affinity DataIC50: 14nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593492(US11578066, Compound I-184 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 14nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593470(US11578066, Compound I-162 | N-[5-(difluoromethoxy...)
Affinity DataIC50: 14.4nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593496(US11578066, Compound I-188 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 15.1nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593452(US11578066, Compound I-143 | N-(5-cyanopyridin-3-y...)
Affinity DataIC50: 15.3nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593522(US11578066, Compound I-214 | N-({5-[5-(difluoromet...)
Affinity DataIC50: 15.4nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593513(US11578066, Compound I-205 | N-(5-chloropyridin-3-...)
Affinity DataIC50: 15.9nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593317(US11578066, Compound I-5 | N-((5-(5-(difluoromethy...)
Affinity DataIC50: 16nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2024
Entry Details
Go to US Patent

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