Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 12235
TargetHistone deacetylase 6(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 12nMAssay Description:The CPP assay was performed 6 h later under the ad libitum feeding condition (n=10 mice for both the Vehicle- and ACY775-treated groups). CPP assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 268nMAssay Description:The CPP assay was performed 6 h later under the ad libitum feeding condition (n=10 mice for both the Vehicle- and ACY775-treated groups). CPP assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 530nMAssay Description:The CPP assay was performed 6 h later under the ad libitum feeding condition (n=10 mice for both the Vehicle- and ACY775-treated groups). CPP assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 850nMAssay Description:The CPP assay was performed 6 h later under the ad libitum feeding condition (n=10 mice for both the Vehicle- and ACY775-treated groups). CPP assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent