Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 12183
TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684691(US20240228490, Example 3 | 3-Ethyl-7-((4-(8-(methy...)
Affinity DataIC50: 0.400nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684706(5-(1-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.600nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684706(5-(1-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.600nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684690(US20240228490, Example 2 | 5-(1-((7-Ethyl-6-oxo-5,...)
Affinity DataIC50: 0.760nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM595739(US11591331, Example 64 | US20240228490, Example 45)
Affinity DataIC50: 0.800nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684701(US20240228490, Example 36 | US20240228490, Example...)
Affinity DataIC50: 0.800nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684711(US20240228490, Example 59 | N-(1-Cyanocyclopropyl)...)
Affinity DataIC50: 0.800nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684710(US20240228490, Example 58 | N-(Cyanomethyl)-1̸...)
Affinity DataIC50: 0.900nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684717(US20240228490, Example 81 | 1′-((7-Ethyl-6-o...)
Affinity DataIC50: 0.900nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684700(US20240228490, Example 33 | 4-(1-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 0.910nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM595701(US11591331, Example 8 | US20240228490, Example 1 |...)
Affinity DataIC50: 0.930nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684707(US20240228490, Example 53 | 7-((4-(1,5-Dimethyl-1H...)
Affinity DataIC50: 0.960nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684696(US20240228490, Example 29 | N-Cyclopropyl-1′...)
Affinity DataIC50: 0.980nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684698(US20240228490, Example 31 | (S)-1′-((7-Ethyl...)
Affinity DataIC50: 1nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684699(US20240228490, Example 32 | (R)-1′-((7-Ethyl...)
Affinity DataIC50: 1nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684701(US20240228490, Example 36 | US20240228490, Example...)
Affinity DataIC50: 1nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684708(US20240228490, Example 56 | 2-Chloro-1′-((7-...)
Affinity DataIC50: 1.30nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684704(US20240228490, Example 42 | 1′-((5-Cyano-3-e...)
Affinity DataIC50: 1.30nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684697(US20240228490, Example 30 | 1′-((7-Ethyl-6-o...)
Affinity DataIC50: 1.40nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684719(US20240228490, Example 83 | 1′-((7-Ethyl-6-o...)
Affinity DataIC50: 1.40nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684701(US20240228490, Example 36 | US20240228490, Example...)
Affinity DataIC50: 1.60nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684695(US20240228490, Example 24 | 3-Ethyl-7-((4-(2-methy...)
Affinity DataIC50: 1.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684713(US20240228490, Example 66 | 4-(1-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 1.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684727(US20240228490, Example 93 | 1′-(1-(7-Ethyl-6...)
Affinity DataIC50: 2.10nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684714(US20240228490, Example 67 | 4-(1-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 2.10nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684712(US20240228490, Example 65 | 3-Chloro-4-(1-((7-ethy...)
Affinity DataIC50: 2.20nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684720(US20240228490, Example 84 | N-Methyl-1′-((6-...)
Affinity DataIC50: 2.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684725(US20240228490, Example 90 | 1′-((3-Ethyl-2-o...)
Affinity DataIC50: 2.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684709(US20240228490, Example 57 | N-Cyano-1′-((7-e...)
Affinity DataIC50: 2.80nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684692(US20240228490, Example 6 | 3-Ethyl-7-((4-(2-methyl...)
Affinity DataIC50: 2.90nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684726(US20240228490, Example 91 | 1′-((3-Ethyl-2,4...)
Affinity DataIC50: 3nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684715(US20240228490, Example 79 | 5-(4-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 3.30nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684694(US20240228490, Example 23 | 7-((4-(1H-Pyrrolo[2,3-...)
Affinity DataIC50: 3.30nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684721(US20240228490, Example 85 | 2-Chloro-1′-((3-...)
Affinity DataIC50: 3.5nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684693(US20240228490, Example 17 | 3-Ethyl-7-((4-(1-oxois...)
Affinity DataIC50: 4.5nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684723(US20240228490, Example 87 | 2-Chloro-1′-((2-...)
Affinity DataIC50: 4.90nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684716(US20240228490, Example 80 | 6-(4-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 5nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684724(US20240228490, Example 88 | 1′-((2-Ethyl-3-o...)
Affinity DataIC50: 5nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684722(US20240228490, Example 86 | 1′-((3-Ethyl-2-o...)
Affinity DataIC50: 5.10nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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