Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 12218
TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM685859(US12043625, Example 1.13 | US12043625, Ex. 1.13)
Affinity DataIC50: 2nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM685851(US12043625, Ex. 1.05 | US12043625, Example 1.05)
Affinity DataIC50: 2nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688400(US20240189315, Ex. 4.04 of PCT/EP2022/062480) | US...)
Affinity DataIC50: 2nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688363(US20240189315, Example 11)
Affinity DataIC50: 2.80nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM685883(US12043625, Example 2.12 | US12043625, Ex. 2.12)
Affinity DataIC50: 3nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688392(US20240189315, Example 38)
Affinity DataIC50: 3nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688391(US20240189315, Example 37)
Affinity DataIC50: 3nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688404(US20240189315, Ex. 1.12 of PCT/EP2022/062480) | US...)
Affinity DataIC50: 3nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688356(US20240189315, Example 04 | (1R,9S,11S,34S)-4-chlo...)
Affinity DataIC50: 3.90nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688375(US20240189315, Example 21)
Affinity DataIC50: 5nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688386(US20240189315, Example 32)
Affinity DataIC50: 5nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688402(US20240189315, Ex. 1.10 of PCT/EP2022/062480) | US...)
Affinity DataIC50: 5nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688387(US20240189315, Example 33)
Affinity DataIC50: 5nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688381(US20240189315, Example 27)
Affinity DataIC50: 5nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688370(US20240189315, Example 18)
Affinity DataIC50: 6nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688379(US20240189315, Example 25)
Affinity DataIC50: 7nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688390(US20240189315, Example 36)
Affinity DataIC50: 7nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
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TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688373(US20240189315, Example 20.02)
Affinity DataIC50: 7nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688385(US20240189315, Example 31)
Affinity DataIC50: 7nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688382(US20240189315, Example 28)
Affinity DataIC50: 7nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688384(US20240189315, Example 30)
Affinity DataIC50: 7nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688355(US20240189315, Example 03 | (1R,9S,11S,34S)-4-Chlo...)
Affinity DataIC50: 7.5nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688388(US20240189315, Example 34)
Affinity DataIC50: 8nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688371(US20240189315, Example 19)
Affinity DataIC50: 8nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688406(US20240189315, Ex. 3.14 of PCT/EP2022/062480) | US...)
Affinity DataIC50: 11nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688368(US20240189315, Example 16)
Affinity DataIC50: 11nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688367(US20240189315, Example 15)
Affinity DataIC50: 11nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688377(US20240189315, Example 23)
Affinity DataIC50: 12nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688357(US20240189315, Example 05 | (1R,9S,11S,34S)-4-chlo...)
Affinity DataIC50: 12nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688369(US20240189315, Example 17)
Affinity DataIC50: 13nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688383(US20240189315, Example 29)
Affinity DataIC50: 14nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688366(US20240189315, Example 14)
Affinity DataIC50: 15nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688364(US20240189315, Example 12)
Affinity DataIC50: 17nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688354(US20240189315, Example 02 | (1R,9S,11S,34S)-4-chlo...)
Affinity DataIC50: 17nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688380(US20240189315, Example 26)
Affinity DataIC50: 18nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688374(US20240189315, Example 20.03)
Affinity DataIC50: 18nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688358(US20240189315, Example 06)
Affinity DataIC50: 18nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688372(US20240189315, Example 20.01)
Affinity DataIC50: 18nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688360(US20240189315, Example 08)
Affinity DataIC50: 22nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688365(US20240189315, Example 13)
Affinity DataIC50: 22nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688353(US20240189315, Example 01)
Affinity DataIC50: 25nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688389(US20240189315, Example 35)
Affinity DataIC50: 27nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688378(US20240189315, Example 24)
Affinity DataIC50: 28nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688361(US20240189315, Example 09)
Affinity DataIC50: 45nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688376(US20240189315, Example 22)
Affinity DataIC50: 45nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM685903(WO2020/142729, Example 25)
Affinity DataIC50: 55nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688398(US20240189315, Compound 5, WO 2022/174012 | BBL010...)
Affinity DataIC50: 55nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688362(US20240189315, Example 10)
Affinity DataIC50: 68nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM688359(US20240189315, Example 07)
Affinity DataIC50: 100nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM685906(WO2020/142729, Example 58)
Affinity DataIC50: 320nMAssay Description:in vitro human biochemical cGAS inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

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