Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 12091
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50496943(CHEMBL3236471 | US20240174621, Example AR-25)
Affinity DataKd:  0.300nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  1.20E+4nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase CSK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  1.21E+3nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  190nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  119nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677079(US20240174621, Example AR-31 | WO2012118492, Examp...)
Affinity DataKd:  45.9nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  1.04E+4nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase CSK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  8.01E+3nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  822nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  504nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677078(US20240174621, Example AR-30 | WO2012118492, Examp...)
Affinity DataKd:  174nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50496943(CHEMBL3236471 | US20240174621, Example AR-25)
Affinity DataKd: >4.00E+4nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase CSK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50496943(CHEMBL3236471 | US20240174621, Example AR-25)
Affinity DataKd: >4.00E+4nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677074(US20240174621, Example 1 | (3R)-N-[2-cyano-4-fluor...)
Affinity DataKd:  0.600nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50496943(CHEMBL3236471 | US20240174621, Example AR-25)
Affinity DataKd:  0.200nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50496943(CHEMBL3236471 | US20240174621, Example AR-25)
Affinity DataKd:  0.100nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677076(US20240174621, Example 2 | (3S)-N-[2-cyano-4-fluor...)
Affinity DataKd:  2.01E+4nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase CSK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677076(US20240174621, Example 2 | (3S)-N-[2-cyano-4-fluor...)
Affinity DataKd:  9.16E+3nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677076(US20240174621, Example 2 | (3S)-N-[2-cyano-4-fluor...)
Affinity DataKd:  1.20nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677076(US20240174621, Example 2 | (3S)-N-[2-cyano-4-fluor...)
Affinity DataKd:  0.900nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677076(US20240174621, Example 2 | (3S)-N-[2-cyano-4-fluor...)
Affinity DataKd:  1.30nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677074(US20240174621, Example 1 | (3R)-N-[2-cyano-4-fluor...)
Affinity DataKd:  4.00E+4nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase CSK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677074(US20240174621, Example 1 | (3R)-N-[2-cyano-4-fluor...)
Affinity DataKd:  2.33E+4nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677074(US20240174621, Example 1 | (3R)-N-[2-cyano-4-fluor...)
Affinity DataKd:  1.70nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM677074(US20240174621, Example 1 | (3R)-N-[2-cyano-4-fluor...)
Affinity DataKd:  1.20nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
Go to US Patent