Compile Data Set for Download or QSAR
Report error Found 141 Enz. Inhib. hit(s) with all data for entry = 12079
TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676804(US20240166660, Compound B1)
Affinity DataIC50: 3nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676897(US20240166660, Compound B94 | US20240166660, Compo...)
Affinity DataIC50: 3.26nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676844(US20240166660, Compound B41)
Affinity DataIC50: 3.80nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676832(US20240166660, Compound B29)
Affinity DataIC50: 4.51nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676814(US20240166660, Compound B11 | US20240166660, Compo...)
Affinity DataIC50: 4.60nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676869(US20240166660, Compound B66 | US20240166660, Compo...)
Affinity DataIC50: 4.60nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676897(US20240166660, Compound B94 | US20240166660, Compo...)
Affinity DataIC50: 4.63nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676807(US20240166660, Compound B4)
Affinity DataIC50: 4.70nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676790(US20240166660, Compound A21)
Affinity DataIC50: 5nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676885(US20240166660, Compound B82)
Affinity DataIC50: 6.20nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676806(US20240166660, Compound B3)
Affinity DataIC50: 6.5nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676903(US20240166660, Compound B100 | US20240166660, Comp...)
Affinity DataIC50: 6.53nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676906(US20240166660, Compound B103)
Affinity DataIC50: 6.95nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676814(US20240166660, Compound B11 | US20240166660, Compo...)
Affinity DataIC50: 7.81nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676808(US20240166660, Compound B5)
Affinity DataIC50: 7.90nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676840(US20240166660, Compound B37)
Affinity DataIC50: 8nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676907(US20240166660, Compound B104 | US20240166660, Comp...)
Affinity DataIC50: 8.16nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676838(US20240166660, Compound B35)
Affinity DataIC50: 8.40nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676798(US20240166660, Compound A29)
Affinity DataIC50: 9.30nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676869(US20240166660, Compound B66 | US20240166660, Compo...)
Affinity DataIC50: 9.30nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676897(US20240166660, Compound B94 | US20240166660, Compo...)
Affinity DataIC50: 9.54nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676833(US20240166660, Compound B30)
Affinity DataIC50: 9.60nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676795(US20240166660, Compound A26)
Affinity DataIC50: 9.90nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676896(US20240166660, Compound B93)
Affinity DataIC50: 11nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676897(US20240166660, Compound B94 | US20240166660, Compo...)
Affinity DataIC50: 11.5nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676801(US20240166660, Compound A32 | US20240166660, Compo...)
Affinity DataIC50: 12nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676881(US20240166660, Compound B78)
Affinity DataIC50: 12nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676846(US20240166660, Compound B43)
Affinity DataIC50: 13nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676843(US20240166660, Compound B40)
Affinity DataIC50: 14nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676851(US20240166660, Compound B48)
Affinity DataIC50: 14nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676789(US20240166660, Compound A20)
Affinity DataIC50: 14.9nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676893(US20240166660, Compound B90 | US20240166660, Compo...)
Affinity DataIC50: 15nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676794(US20240166660, Compound A25)
Affinity DataIC50: 15.5nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676823(US20240166660, Compound B20)
Affinity DataIC50: 16nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676903(US20240166660, Compound B100 | US20240166660, Comp...)
Affinity DataIC50: 18nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676889(US20240166660, Compound B86)
Affinity DataIC50: 19nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676850(US20240166660, Compound B47)
Affinity DataIC50: 25nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676856(US20240166660, Compound B53)
Affinity DataIC50: 28nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676868(US20240166660, Compound B65)
Affinity DataIC50: 30nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676786(US20240166660, Compound A17)
Affinity DataIC50: 31.7nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676809(US20240166660, Compound B6)
Affinity DataIC50: 34nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676873(US20240166660, Compound B70)
Affinity DataIC50: 35nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676893(US20240166660, Compound B90 | US20240166660, Compo...)
Affinity DataIC50: 37nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676787(US20240166660, Compound A18)
Affinity DataIC50: 37.8nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676857(US20240166660, Compound B54)
Affinity DataIC50: 40nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676845(US20240166660, Compound B42)
Affinity DataIC50: 43nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676776(US20240166660, Compound A7)
Affinity DataIC50: 43.1nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676878(US20240166660, Compound B75)
Affinity DataIC50: 44nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676839(US20240166660, Compound B36)
Affinity DataIC50: 47nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
BeiGene Switzerland GmbH

US Patent
LigandPNGBDBM676884(US20240166660, Compound B81)
Affinity DataIC50: 48nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

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