Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 12023
TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670920(US20240140962, Compound 4)
Affinity DataIC50: 1nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670924(US20240140962, Compound 8)
Affinity DataIC50: 1.70nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670921(US20240140962, Compound 5)
Affinity DataIC50: 2.60nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670932(US20240140962, Compound 20)
Affinity DataIC50: 2.80nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670923(US20240140962, Compound 7)
Affinity DataIC50: 3nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670925(US20240140962, Compound 12)
Affinity DataIC50: 4nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670918(US20240140962, Compound 2)
Affinity DataIC50: 4.20nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670931(US20240140962, Compound 18)
Affinity DataIC50: 4.30nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670917(US20240140962, Compound 1)
Affinity DataIC50: 4.40nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670926(US20240140962, Compound 13)
Affinity DataIC50: 4.90nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670919(US20240140962, Compound 3)
Affinity DataIC50: 5nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670929(US20240140962, Compound 16)
Affinity DataIC50: 5.30nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670930(US20240140962, Compound 17)
Affinity DataIC50: 5.90nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670928(US20240140962, Compound 15)
Affinity DataIC50: 6.40nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670922(US20240140962, Compound 6)
Affinity DataIC50: 6.90nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
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TargetSerine/threonine-protein kinase PLK1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM670927(US20240140962, Compound 14)
Affinity DataIC50: 7.30nMAssay Description:The 33P isotope-labeled kinase activity assay (Reaction Biology Corp) was used to determine the IC50 value to evaluate the inhibitory ability of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent